Browsing Chemistry by Subject "Bicyclo[1.1.1]pentane"
Now showing items 1-3 of 3
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Bridging and Conformational Control of Porphyrin Units through Non-Traditional Rigid Scaffolds
(2020)Connecting two porphyrin units in a rigid linear fashion, without any undesired electron delocalization or communication between the chromophores, remains a synthetic challenge. Herein, a broad library of functionally ... -
An Insight into Non-Covalent Interactions on the Bicyclo[1.1.1]pentane Scaffold
(2021)Bicyclo[1.1.1]pentane (BCP) is studied extensively as a bioisosteric component of drugs. Not found in nature, this molecular unit approximates the distance of a para-disubstituted benzene which is replaced in medicines as ... -
Methods Development for the Synthesis of Biologically Relevant Porphyrins and Porphyrin Rigid Linker Arrays
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)This research focuses on two main aspects: The synthesis of new derivatives of naturally occurring porphyrins and the preparation of non-natural chromophore-rigid linker conjugates as potential bioisosteres and mimics of ...