Pharmacy and Pharmaceutical Sciences (Scholarly Publications)
Browse by
Recent Submissions
-
Guided by theory, grounded in practice: evidence-based development of teaching resources for multisite interprofessional education
(Trinity College Dublin, 2023) -
Chemotherapy drug scheduling for the induction treatment of patients with acute myeloid leukemia
(2014)Leukemia is an immediately life-threatening cancer wherein immature blood cells are overproduced, accumulate in the bone marrow (BM) and blood and causes immune and blood system failure. Treatment with chemotherapy can ... -
Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds
(2011)Cord blood expansion ex vivo can be achieved in liquid suspension through the addition of cytokines at the expense of often undesirable cell differentiation. In order to derive a cytokine-free dynamic culture system, we ... -
The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia
(2010)Acute myeloid leukaemia (AML) is a cancer of haematopoietic cells that develops in three-dimensional (3-D) bone marrow niches in vivo. The study of AML has been hampered by lack of appropriate ex vivo models that mimic ... -
Dynamic human erythropoiesis in a three-dimensional perfusion bone marrow biomimicry
(2019)Traditional culture systems for human erythropoiesis lack microenvironmental niches, spatial marrow gradients and dense cellularity rendering them incapable of effectively translating marrow physiology ex vivo. Herein, a ...