Browsing Mechanical & Manufacturing Eng (Theses and Dissertations) by Subject "Mechanical Engineering, Ph.D."
Now showing items 1-18 of 18
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A forward advancing wave expansion method for numerical solution of large-scale sound propagation problems
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2007)The study of atmospheric somid propagation has become an important subject since noise polhition problems emerged as a highly relevant matter in several areas such as sociology, economics, regulations and standards. Modelling ... -
An investigation into the causes of higher rates of restenosis in peripheral arteries compared with coronary arteries following stenting
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2010)The use of stenting in peripheral arteries has been limited by rates of in-stent restenosis and stent fracture considerably higher than seen in coronary arteries. Traditional balloon expandable stainless steel stents were ... -
Bubble impingement and the mechanisms of heat transfer enhancement
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2014)Fluid agitation and mixing ensuing from two phase flow has an important role to play within two phase flow heat exchangers, which are at the forefront of energy conversion. Within these environments, vapour bubbles may ... -
Composition and mechanical properties of osteoarthritic subchondral trabecular tibial bone
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2007)Osteoarthritis is a disease that has been characterised historically by the focal destruction of cartilaginous tissue and hence, is defined as such. However, recent investigations have brought this pathology into contention. ... -
Computational and experimental investigation of bone cell response to mechanical stimuli
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2006)The importance of mechanical loading in maintaining bone quality is well illustrated by the drastic effects of its absence in, for example, microgravity, cast immobilisation or paraplegia. The mechanisms underlying adaptation ... -
Computational modelling of bone regeneration using a three-dimensional lattice approach
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2009)Mechano-regulatory theories are indispensable for developing and understanding how mechanical forces modulate morphological and structural fitness of skeletal tissues. These theories have been incorporated into computational ... -
Computational simulation of the mechanobiological response of arterial tissue
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2012)Ischaemic heart disease, causing restriction of arterial blood flow to the heart tissue, can be treated with mechanical revascularisation treatments such as balloon angioplasty and stent implantation. One remaining limitation ... -
Computer approaches to total hip replacement evaluation just prior to operation
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 1999)The surgical operation of total hip replacement (THR) is, after 30 years, regarded as a successful medical procedure. The average life of an artificial hip has, however, remained at about 15 years for more than a decade, ... -
Design, manufacture, modelling and testing of surface acoustic wave strain sensors
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2008)There is an increasing demand for multi-sensor strain measurement systems, particularly those which incorporate wireless sensors. A possible application of such a system is the Real-Time Weigh-In-Motion (RTWIM) of heavy ... -
Failure of cemented hip implants under complex loading : experimental and numerical analysis
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2004)A new generation of experimental pre-clinical testing methods for cemented hip replacement femoral components have been proposed, and preliminarily validated by comparing a 'good' prosthesis design with a 'bad' prosthesis ... -
Finite element and experimental analysis of the micro-form rolling process
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2007)The observations made during this research which, to the best knowledge of the author have not been previously mentioned in literature, were as follows: -- Loss of contact between the die and workpiece when rolling small ... -
Mechanoregulation of bone formation : from embryogenesis to evolution
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2007)In summary the author's thesis is that biophysical stimuli mechanoregulate ossification events through the action of mechanosensitive genes, where mechanoregulation is an ontogenetic process which has evolved. The author ... -
Prediciton of fatigue failure in engineering components using the finite element method
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2000)Prediction of fatigue failure in engineering artefects is becoming increasingly important as we enter the third millennium; more catastrophic fatigue failures will occur as engineers push the limits of design even further ... -
Simulation of tissue differentation during fracture healing
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2001)Fracture healing is a complex biological process during which, repair of the damaged tissues occurs so efficiently that the initial strength and anatomy of the bone are restored. Mechanical loading is believed to greatly ... -
The developement of novel scaffolds for tissue engineering with a range of structural and mechanical properties
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2009)Tissue engineering (or regenerative medicine) is defined as the application of scientific principles to the synthesis of living tissues using bioreactors, cells, scaffolds, growth factors, or a combination (Rose and Oreffo, ... -
The effect of bone turnover on bone quality and material properties
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2008)Coined in French in the 1820s as a description of a pathological state of bone tissue, the term osteoporosis made its way into the English language only in the 20th century. Unlike other medical concepts, which have not ... -
The relationship between blood perfusion and thermal measurements at the skin surface
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2006)Blood perfusion is defined as the volumetric flow rate of blood through a given volume of tissue. Blood perfusion measurements are an important clinical indicator for many medical conditions but to date there is no cost ...
