Browsing Clinical Medicine (Scholarly Publications) by Sponsor "Health Research Board"
Now showing items 1-8 of 8
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Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
(American Society for Clinical Nutrition, 2005)Background: Little is known about the interactions between choline and folate and homocysteine metabolism during pregnancy despite the facts that pregnancy places considerable stress on maternal folate and choline stores ... -
A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma
(Nature, 2001)The incidence of oesophageal adenocarcinoma is rising; to date, no susceptibility genes have been identified. p73, a novel p53 homologue, maps to chromosome 1p36, a region commonly deleted in oesophageal cancers. p73 shares ... -
Confirmation of the R653Q polymorphism of the trifunctional C1-synthase enzyme as a maternal risk for neural tube defects in the Irish population.
(Nature Publishing Group, 2006)The risk of neural tube defects (NTDs) is known to have a significant genetic component that could act through either the NTD patient and/or maternal genotype. The success of folic acid supplementation in NTD prevention ... -
Endothelin inhibitors for advanced prostate cancer
(John Wiley, 2011)This is the protocol for a review and there is no abstract. The objectives are as follows: Our review aims to determine the effectiveness and adverse effects of endothelin inhibitors for advanced prostate cancer. The ... -
Estimation of coherence using the median is robust against EEG artefacts
(2017)Coherence is a mathematical measure of correlation in the frequency domain, commonly used to quantify the oscillatory synchrony of bio-signals such as the electroencephalogram (EEG). In biomedical applications, such as ... -
Folate-related gene polymorphisms as risk factors for cleft lip and cleft palate.
(John Wiley, 2008)BACKGROUND?Cleft lip with or without cleft palate (CLP) and cleft palate only (CPO) have an inherited component and, many studies suggest, a relationship with folate. Attempts to find folaterelated genes associated with ... -
Impact of the MTHFR C677T polymorphism on risk of neural tube defects:case-control study
(BMJ, 2004)Homozygosity for the T allele of the C677T polymorphism of the gene encoding the folate dependent enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR) is a risk factor for neural tube defects.1 Both the homozygous (TT) ... -
A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss.
(Oxford University Press, 2005)Low maternal folate or vitamin B12 status has been implicated in numerous pregnancy complications including spontaneous abortion. The primary aim of this study was to test a polymorphism within the trifunctional folate ...