Browsing Histopathology & Morbid Anatomy (Scholarly Publications) by Author "GALLAGHER, MICHAEL"
Now showing items 1-10 of 10
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Catching Moving Targets: Cancer Stem Cell Targets, Therapy-Resistance & Considerations for Clinical Targeting
GALLAGHER, MICHAEL (2017) -
CD10-/ALDH- cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell network. Cell Death & Disease
GALLAGHER, MICHAEL; O'TOOLE, SHARON; BATES, MARK (2017) -
Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention.
O'LEARY, JOHN; GALLAGHER, MICHAEL (2014)Despite decades of research, ovarian cancer is still associated with unacceptably high mortality rates, which must be addressed by novel therapeutic approaches. One avenue through which this may be achieved is targeting ... -
Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer
SHEILS, ORLA; O'LEARY, JOHN; GALLAGHER, MICHAEL; SPILLANE, CATHY (2015)Background: Ovarian cancer is associated with poor long-term survival due to late diagnosis and development of chemoresistance. Tumour hypoxia is associated with many features of tumour aggressiveness including increased ... -
An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines.
SHEILS, ORLA; O'LEARY, JOHN; GALLAGHER, MICHAEL; SPILLANE, CATHY (2014) -
The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.
MARTIN, CARA; SHEILS, ORLA; SMYTH, PAUL; FINN, STEPHEN; O'LEARY, JOHN; GALLAGHER, MICHAEL; BATES, MARK; SPILLANE, CATHY (2014)The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential ... -
Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients.
SMYTH, PAUL; MARTIN, CARA; MCINERNEY, JAMIE KEVIN; ELBARUNI, SALAH AMRU; O'LEARY, JOHN; SALLEY, YVONNE; VENCKEN, SEBASTIAN; O'TOOLE, SHARON; AHERNE, SINEAD; SHEILS, ORLA; GALLAGHER, MICHAEL (2009)Background: Tumours with high proportions of differentiated cells are considered to be of a lower grade to those containing high proportions of undifferentiated cells. This property may be linked to the differentiation ... -
Targeting aldehyde dehygrogenase 1 (ALDH1) to circumvent cisplatin resistance in NSCLC
GALLAGHER, MICHAEL (2017)