Browsing Histopathology & Morbid Anatomy (Scholarly Publications) by Author "FINN, STEPHEN"
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Application of statistical process control to qualitative molecular diagnostic assays.
O'BRIEN, CATHAL; FINN, STEPHEN (2014)Modern pathology laboratories and in particular high throughput laboratories such as clinical chemistry have developed a reliable system for statistical process control (SPC). Such a system is absent from the majority of ... -
B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression.
FINN, STEPHEN (2010)Although B-Raf(V600E) is the most common somatic mutation in papillary thyroid carcinoma (PTC), how it induces tumor aggressiveness is not fully understood. Using gene set enrichment analysis and in vitro and in vivo ... -
Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer.
FINN, STEPHEN (2009)The identification of biomarkers that distinguish between aggressive and indolent forms of prostate cancer (PCa) is crucial for diagnosis and treatment. In this study, we used cultured cells derived from prostate tissue ... -
Fatty acid synthase polymorphisms, tumor expression, body mass index, prostate cancer risk, and survival.
FINN, STEPHEN (2010)BACKGROUND: Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN. METHODS: We used immortalized human prostate ... -
Gleason score and lethal prostate cancer: does 3 + 4 = 4 + 3?
FINN, STEPHEN (2009)PURPOSE Gleason grading is an important predictor of prostate cancer (PCa) outcomes. Studies using surrogate PCa end points suggest outcomes for Gleason score (GS) 7 cancers vary according to the predominance of pattern ... -
Molecular testing in oncology: Problems, pitfalls and progress.
FINN, STEPHEN; O'LEARY, JOHN (2014)Recent advances in the understanding of the molecular basis of cancer and the development of molecular diagnostics based on this knowledge have done much to progress the fields of oncology and pathology. Technological ... -
The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.
MARTIN, CARA; SHEILS, ORLA; SMYTH, PAUL; FINN, STEPHEN; O'LEARY, JOHN; GALLAGHER, MICHAEL; BATES, MARK; SPILLANE, CATHY (2014)The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential ...