Browsing Medical Gerontology (Scholarly Publications) by Sponsor "Health Research Board (HRB)"
Now showing items 1-19 of 19
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Age-related normative changes in cerebral perfusion: data from The Irish Longitudinal Study on Ageing (TILDA)
(2021)Objective: To establish normative reference values for total grey matter cerebral blood flow (CBFGM) measured using pseudo-continuous arterial spin labelling (pCASL) MRI in a large cohort of community-dwelling adults aged ... -
Altered lives in a time of crisis: The impact of the COVID-19 pandemic on the lives of older adults in Ireland. Findings from The Irish Longitudinal Study on Ageing
(TILDA, 2021)The ongoing pandemic of SARS-CoV-2, a novel coronavirus that causes COVID-19 infection and disease, is threatening healthcare systems globally as well as in Ireland. (1) The COVID-19 pandemic, and public health-associated ... -
Building resilience and reversing frailty: a randomised controlled trial of a primary care intervention for older adults
(2023)Background: There is a need for effective primary care interventions that help older people combat frailty and build resilience. Objective: To study the effectiveness of an optimised exercise and dietary protein ... -
Clustering of behavioural symptoms and their associations with cognitive decline in older adults
(2020)Objectives: To examine (i) the clustering of reduced falls-efficacy, social withdrawal and physical activity withdrawal in Irish adults aged 50 years and older, and (ii) the concurrent and prospective associations of these ... -
How does socio-economic position (SEP) get biologically embedded? A comparison of allostatic load and the epigenetic clock(s)
(Elsevier, 2019)Individuals of lower socio-economic position (SEP) carry a heavier burden of disease and morbidity and live shorter lives on average compared with their more advantaged counterparts. This has sparked research interest in ... -
The Importance of Proximity to Death in Modelling Community Medication Expenditures for Older People: Evidence From New Zealand
(2014)BACKGROUND: Concerns about the long-term sustainability of health care expenditures (HCEs), particularly prescribing expenditures, has become an important policy issue in most developed countries. Previous studies suggest ... -
In their own words: The voices of Older Irish people in the COVID-19 pandemic
(The Irish Longitudinal Study on Ageing, Trinity College Dublin, 2021)Since COVID-19 was declared an international pandemic by the World Health Organisation (WHO) in March 2020 (HSE, 2021), older people have carried the greatest burden of serious infection and death from the virus. ... -
The Lasting Legacy of Childhood Adversity for Disease Risk In Later Life
(2015)Objective: There has been an increased interest in the role of the childhood social environment in the etiology of adult diseases in recent years. The present study examines whether the experience of adversity during ... -
Maternal educational inequalities in measured body mass index trajectories in three European countries
(2019)Background: Social inequalities in the prevalence of childhood overweight and obesity are well‐established, but less is known about when the social gradient first emerges and how it evolves across childhood and ... -
Network Physiology in Aging and Frailty: The Grand Challenge of Physiological Reserve in Older Adults
(2021)In this Specialty Grand Challenge, we outline our vision of the current challenges in the field of Network Physiology as applied to aging and frailty. An expected development in this field for the 21st century is the ... -
Older adults shielding at home
(TILDA, 2020)Two thirds of adults aged 60 and older agreed or strongly agreed with shielding. Interestingly, a higher percentage of those most affected by policy, the over 70s, agreed with it. Whether people lived alone or with others ... -
Older adults' experience of ageism during the COVID-19 pandemic
(TILDA, 2020)Despite the fact that the vast majority of older adults are not physically, cognitively or mentally impaired, age-related stereotypes persist. These stereotypes commonly portray older adults as physically and cognitively ... -
Perceived stress before and during the COVID-19 pandemic
(2020)Since the beginning of the COVID-19 pandemic, perceived stress has increased significantly among older adults. This increase will likely negatively affect both physical and psychological wellbeing among this population. ... -
Preparing for COVID-19 vaccination: important learnings from the Irish Longitudinal Study on Ageing (TILDA)
(TILDA, 2020)This report brings together important information on vaccinations among adults aged 60 years and older learned from the Irish Longitudinal Study on Ageing (TILDA), which can inform the rollout of COVID-19 vaccinations. The ... -
Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis.
(2019)Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive to the accumulation of deleterious exposures across the ... -
Study protocol for TILDA COVID-19 survey. Altered lives in a time of crisis: preparing for recovery from the impact of the COVID-19 pandemic on the lives of older adults
(2021)Background: Older adults are the most at-risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and among the most affected by measures put in place to prevent the spread of the virus. While the ... -
What Explains Socioeconomic Differences in the Speed of Heart Rate Recovery to Postural Challenge?
(2017)Background: Much recent work has focused on the value of heart rate recovery (HRR) as a marker of cardiovascular health and a predictor of mortality. This article explores socioeconomic variation in HRR following exposure ...