Browsing Medical Gerontology (Scholarly Publications) by Title
Now showing items 4-23 of 344
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ACE gene I/D polymorphism and severity of SARS-CoV-2 infection in hospitalized patients: a metanalysis
(2021)Background Hypertension and type 2 diabetes increase the risk of severe SARS-CoV-2 infection. On the other hand, homozygous ACE deletion polymorphism (DD) has been associated with these two diseases and risk of acute ... -
Admissions for Orthostatic Hypotension: an Analysis of NHS England Hospital Episode Statistics Data
(2019)Objectives To determine whether admissions for orthostatic hypotension (OH) and its consequences, such as falls, have changed over the past 10 years in the National Health Service (NHS) England. Setting Data from NHS ... -
The aesthetic and cultural pursuits of patients with stroke
(2013)Background: There has been an increasing interest in the arts in health care, with a suggestion that the arts and aesthetics can augment patient outcomes in stroke and other illnesses. Designing such programmes requires ... -
AF is associated with self-reported syncope and falls in a general population cohort.
(2015)Background: syncope is an important, but underestimated clinical problem in older persons. It is often overlooked in clinical practice or mistaken for falls. Atrial fibrillation (AF) is the most common cardiac arrhythmia, ... -
Age-related normative changes in cerebral perfusion: data from The Irish Longitudinal Study on Ageing (TILDA)
(2021)Objective: To establish normative reference values for total grey matter cerebral blood flow (CBFGM) measured using pseudo-continuous arterial spin labelling (pCASL) MRI in a large cohort of community-dwelling adults aged ... -
Ageing, cognitive disorders and professional practice.
(2013)Background: the workforce is ageing. The contribution of older workers is considerable. Their occupational health profiles differ from those of younger workers. Objective: we wished to establish whether consideration ... -
Ageism in Stroke Rehabilitation Studies
(2014)Background: stroke is predominantly a disease of older people. While age bias has been demonstrated in studies of pharmacological therapeutic interventions in stroke, the extent of discrimination by age in stroke rehabilitation ... -
Alluvial visualization and computation of probabilities of transitions in frailty index states over an 8-year period using multi-state Markov models
(2021)The Frailty Index (FI) is an operationalization of frailty in older adults based on the accumulation of health deficits. FI cut-offs define the non-frail, prefrail and frail states. We described longitudinal transitions ... -
Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology: a study in the MRC-CFAS population neuropathology cohort
(Elsevier, 2011)Impairment of the blood brain barrier (BBB) in human brain ageing and its relationship to Alzheimer-type pathology remains poorly defined. We have investigated the BBB in temporal cortex of brain donations from a ... -
Altered lives in a time of crisis: The impact of the COVID-19 pandemic on the lives of older adults in Ireland. Findings from The Irish Longitudinal Study on Ageing
(TILDA, 2021)The ongoing pandemic of SARS-CoV-2, a novel coronavirus that causes COVID-19 infection and disease, is threatening healthcare systems globally as well as in Ireland. (1) The COVID-19 pandemic, and public health-associated ... -
An alternative method for Frailty Index cut-off points to define frailty categories.
(2013)PURPOSE: the Frailty Index (FI) is a popular operationalization of frailty. FI cut-off points have been proposed to define, regardless of age, frailty categories with increasing risk. Here, an alternative method is ... -
Amnesia for loss of consciousness is common in vasovagal syncope.
(2011)The aim of this study was to determine the prevalence of amnesia for loss of consciousness (A-LOC) in those who have a history suggestive of vasovagal syncope (VVS) and who develop syncope on head-up tilt (HUT) table ... -
Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study
(2020)Background: Some studies have suggested that the insertion(I)/deletion(D) polymorphism of the Angiotensin-Converting Enzyme (ACE) gene may be associated with human longevity, especially in centenarians. However, this ... -
Anticholinergic medications in patients admitted with cognitive impairment and falls (AMiCI). The impact of hospital admission on anticholinergic cognitive medication burden. Results of a multi centre observational study
(2018)What is known and objective: Drugs with anticholinergic properties increase the risk of falls, delirium, chronic cognitive impairment, and mortality and counteract procholinergic medications used in the treatment of dementia. ... -
Antidepressants are Independently Associated with Gait Deficits in Single and Dual Task Conditions
(2015)Objectives This study examined the relationships between late-onset depressive symptoms, antidepressants, and single and dual task gait in older adults. Design Cross-sectional study. Setting The Irish Longitudinal ... -
Antidepressants strongly influence the relationship between depression and heart rate variability: findings from The Irish Longitudinal Study on Ageing (TILDA)
(2015)Background: Heart rate variability (HRV) is known to be reduced in depression; however, is unclear whether this is a consequence of the disorder or due to antidepressant medication. Methods: We analysed data on 4750 ...