Browsing Medical Gerontology (Scholarly Publications) by Sponsor "Science Foundation Ireland (SFI)"
Now showing items 21-40 of 72
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Cognitive function in the prefrailty and frailty syndrome
(2014)OBJECTIVES: To explore the relationship between cognitive function and frailty. DESIGN: A cross-sectional study using data from Wave 1 of The Irish Longitudinal Study on Ageing, a population representative study of ... -
Comparative analysis of frailty identification criteria on continuous non-invasive neurocardiovascular signals during an active stand test in The Irish Longitudinal Study on Ageing (TILDA)
(2023)Frailty is a distinctive health state related to acceleration of biological ageing in which multiple body systems disproportionately lose their in-built reserves. Older people living with frailty are at higher risk of ... -
Comparison of gait speed reserve, usual gait speed, and maximum gait speed of adults aged 50+ in Ireland using explainable machine learning
(2021)Gait speed is a measure of general fitness. Changing from usual (UGS) to maximum (MGS) gait speed requires coordinated action of many body systems. Gait speed reserve (GSR) is defined as MGS–UGS. From a shortlist of 88 ... -
Comprehensive clinical characterisation of brain fog in adults reporting long COVID symptoms
(2022)(1) Introduction: A subset of individuals experiencing long COVID symptoms are affected by ‘brain fog’, a lay term that often refers to general cognitive dysfunction but one that is still poorly characterised. In this ... -
“Dancing with Atoms”: A tribute to Sheila Tinney
(2023)The authors present a short dynamic visualization titled “Dancing with Atoms”, produced in honor of the late Irish mathematical physicist Sheila Tinney (1918--2010), the first Irish-born and -raised woman to receive a ... -
Deep Learning Retinal Image Analysis for the Detection of CKD and Cardiovascular Risk Factors in the General Population
(2022)Background: Retinal blood vessel patterns provide an opportunity to personalize an individuals risk assessment for CKD and cardiovascular risk factors (CVRF). In this study we propose a deep learning (DL) based prediction ... -
Development of a Frailty Index in the Irish Hip Fracture Database
(2022)Introduction In older people, hip fracture can lead to adverse outcomes. Frailty, capturing biological age and vulnerability to stressors, can indicate those at higher risk. We derived a frailty index (FI) in the Irish ... -
Differential Associations Between Two Markers of Probable Sarcopenia and Continuous Orthostatic Hemodynamics in The Irish Longitudinal Study on Ageing
(2022)Background: Sarcopenia and orthostatic hypotension are growing age-related health burdens associated with adverse outcomes including falls. Despite a possible pathophysiological link, the association between the two disorders ... -
Do The Frail Experience More Adverse Events From Intensive Blood Pressure Control? A 2-Year Prospective Study In The Irish Longitudinal Study On Ageing (TILDA)
(2022)Background: The 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) guidelines for management of hypertension in adults aged ≥65 years recommend a blood pressure (BP) treatment target of 130–139/70–79 ... -
Eight orthostatic haemodynamic patterns in The Irish Longitudinal Study on Ageing (TILDA): stability and clinical associations after 4 years
(2021)Previous research cross-sectionally characterised eight morphological systolic blood pres-sure (SBP) active stand (AS) patterns using a clinical clustering approach at Wave 1 (W1) of the IrishLongitudinal Study on Ageing. ... -
Eight-year longitudinal falls trajectories and associations with modifiable risk factors: evidence from The Irish Longitudinal Study on Ageing (TILDA)
(2023)Background: The label 'faller' and the associated stigma may reduce healthcare-seeking behaviours. However, falls are not inevitably progressive and many drivers are modifiable. This observational study described the 8-year ... -
Evaluation of a 3-Item Health Index in Predicting Mortality Risk: A 12-Year Follow-Up Study
(2023)This study was carried out using a large cohort (N = 4265; 416 deceased) of older, community-dwelling adults from The Irish Longitudinal Study on Ageing (TILDA). The study compared the performance of a new 3-item health ... -
Exploring bi-directional temporal associations between timed-up-and-go and cognitive domains in The Irish Longitudinal Study on Ageing (TILDA)
(2022)Introduction: The bi-directional longitudinal associations between mobility and cognition in older adults are poorly understood. Our objective was to study the temporal associations between timed-up-and-go (TUG) and five ... -
Frail by Different Measures: A Comparison of 8-year Mortality in The Irish Longitudinal Study on Ageing (TILDA)
(2021)Purpose: We compared the ability of four frailty identification tools (frailty phenotype: FP; FRAIL scale; 32-item Frailty Index: FI; and Clinical Frailty Scale: CFS) to predict 8-year mortality in TILDA. Methods: We ... -
Frail by four different measures and new adverse events from lower blood pressure control in hypertensive older adults: a 2-year prospective study in The Irish Longitudinal Study on Ageing (TILDA)
(2022)Background: The 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) guidelines for management of hypertension in adults aged ≥65 years recommend a blood pressure (BP) treatment target of 130–139/70–79 ... -
Functional Analysis of Continuous, High-Resolution Measures in Ageing Research: A Demonstration using Cerebral Oxygenation Data from The Irish Longitudinal Study on Ageing
(2020)Background: A shift towards the dynamic measurement of physiologic resilience and improved technology incorporated into experimental paradigms in aging research is producing high-resolution data. Identifying the most ... -
Functional clustering of continuous cardiovascular and brain oxygenation signals during an active stand test in The Irish Longitudinal Study on Ageing (TILDA)
(2023)In this study, we performed K-shape functional clustering of two non-invasive continuous cardiovascular (systolic Blood Pressure: sBP) and brain oxygenation (left frontal lobe Tissue Saturation Index: TSI) times series ... -
Haemodynamic Parameters Underlying the Relationship Between Sarcopenia and Blood Pressure Recovery on Standing
(2023)Background: Sarcopenia, delayed blood pressure (BP) recovery following standing, and orthostatic hypotension (OH) pose significant clinical challenges associated with ageing. While prior studies have established a link ... -
Hospital-associated deconditioning: not only physical, but also cognitive
(2022)Introduction Hospital-associated deconditioning (HAD) or post-hospital syndrome is well recognized as reduced functional performance after an acute hospitalization. Recommendations for the management of HAD are still ...