Browsing Chemistry (Theses and Dissertations) by Author "O'Donovan, Daniel Hillebrand"
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The rational design and synthesis of novel a-2 andrenoceptor antagonists as potential antidepressants
O'Donovan, Daniel Hillebrand (Trinity College (Dublin, Ireland). School of Chemistry, 2011)Depression is one of the leading causes of illness worldwide and has been closely linked to low concentrations of monoaminergic neurotransmitters in the brain. Activation of presynaptic alpha-2 adrenoceptors (a2-AR) by the ...