Browsing Immunology (Scholarly Publications) by Author "Molloy, Eleanor"
Now showing items 1-4 of 4
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Altered distributions and functions of natural killer T cells and γδ T cells in neonates with neonatal encephalopathy, in school-age children at follow-up, and in children with cerebral palsy
Doherty, Derek; Molloy, Eleanor (2021)We enumerated conventional and innate lymphocyte populations in neonates with neonatal encephalopathy (NE), school-age children post-NE, children with cerebral palsy and age-matched controls. Using flow cytometry, we ... -
Altered endotoxin responsiveness in healthy children with Down syndrome.
Roche, Edna; Doherty, Derek; Leahy, Ronan; Molloy, Eleanor; Balfe, Joanne (2018)Background: Down syndrome (DS) is the most common syndromic immunodeficiency with an increased risk of infection, mortality from sepsis, and autoinflammation. Innate immune function is altered in DS and therefore we examined ... -
Increased systemic inflammation in children with Down syndrome
Molloy, Eleanor; Roche, Edna; Leahy, Ronan; Doherty, Derek; Franklin, Orla; Balfe, Joanne; Kelly, Lynne (2020)Children with Down syndrome (DS) develop more infections, have an increased mortality from sepsis and an increased incidence of chronic inflammatory conditions. Cytokine dysregulation may underpin these clinical sequelae ... -
The role of lymphocytes in neonatal encephalopathy.
Doherty, Derek; Molloy, Eleanor (2021)Neonatal encephalopathy is a syndrome characterised by abnormal neurological function often caused by a hypoxic insult during childbirth. Triggers such as hypoxia-ischaemia result in the release of cytokines and chemokines ...