Browsing Immunology (Scholarly Publications) by Author "Lysaght, Joanne"
Now showing items 1-3 of 3
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CD1d expression and invariant natural killer T-cell numbers are reduced in patients with upper gastrointestinal cancers and are further impaired by commonly used chemotherapies
Doherty, Derek; Lysaght, Joanne; Reynolds, John (2020)Esophageal and gastric cancers collectively cause over 1.1 million deaths annually and only 20-30% of patients respond favorably to current therapies. Cellular therapies using invariant natural killer T (iNKT) cells are ... -
Selective effects of radiotherapy on viability and function of invariant natural killer T cells in vitro
Maher, Stephen; Doherty, Derek; Lysaght, Joanne (2020)Background and purpose: Immunotherapies involving the adoptive transfer of ex vivo expanded autologous invariant natural killer (iNKT) cells are a potential option for cancer patients and are under investigation in clinical ... -
Tissue distribution of γδ T cell subsets in oesophageal adenocarcinoma
Murphy, Dearbhla; Lysaght, Joanne; Doherty, Derek; Reynolds, John (2021)The global obesity epidemic is contributing to increased prevalence of diseases fuelled by chronic inflammation, including cancer. Oesophageal adenocarcinoma (OAC) is an obesity-associated malignancy with increasing ...