Browsing by Subject "Nanoparticles"
Now showing items 1-11 of 11
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Benchmark of Nanoparticle Tracking Analysis on Measuring Nanoparticle Sizing and Concentration
(2017)One of the greatest challenges in the manufacturing and development of nanotechnologies is the requirement for robust, reliable, and accurate characterization data. Presented here are the results of an interlaboratory ... -
Biocompatible copolymer formulations to treat glioblastoma multiforme.
(2021)The treatment for glioblastoma multiforme (GBM) has not changed for more than 20 years while the prognosis for the patients is still poor and most of them survive less than 1 year after diagnosis. The standard of care for ... -
Conjugated Quantum Dots Inhibit the Amyloid β (1-42) Fibrillation Process
(2011)Nanoparticles have enormous potential in diagnostic and therapeutic studies. We have demonstarted that the amyloid beta mixed with and conjugated to dihydrolipoic acid (DHLA)-capped CdSe/ZnS quantum dots (QDs) of size ... -
Design and development of a hydrogel formulation with nanoparticles for the treatment of glioblastoma multiforme
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2021)Glioblastoma multiforme (GBM) is the most aggressive form of brain tumours. GBM treatment is challenging because tumours are highly invasive and it is difficult to achieve effective therapeutic doses of drugs into the ... -
Effect on Platelet Function of Metal-Based Nanoparticles Developed for Medical Applications.
(2019)Nanomaterials have been recently introduced as potential diagnostic and therapeutic tools in the medical field. One of the main concerns in relation to the use of nanomaterials in humans is their potential toxicity profile ... -
Interactions of Plasmonic and Dielectric Structures with 2D Materials
(Trinity College Dublin. School of Physics. Discipline of Physics, 2023)Three separate systems of nanoparticles coupled to two-dimensional materials are studied. Each system is investigated both experimentally and numerically with FDTD simulations. The first system involves a nanoparticle-on-mirror ... -
New solid forms of itraconazole and their pharmaceutical applications
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2020)Itraconazole (ITR) is an active pharmaceutical ingredient (API) with a broad-spectrum antifungal activity. This API has a very low solubility, which can hinder its bioavailability after oral administration. In this work, ... -
Polyelectrolyte-stabilised magnetic-plasmonic nanocomposites
(2018)In this work, new magnetic-plasmonic nanocomposites have been developed through the use of two complementary polyelectrolytes–polystyrene sulfonate (PSS) and poly(allylamine hydrochloride) (PAH). PSS, a negatively charged ... -
The rationale and emergence of electroconductive biomaterial scaffolds in cardiac tissue engineering.
(2019)The human heart possesses minimal regenerative potential, which can often lead to chronic heart failure following myocardial infarction. Despite the successes of assistive support devices and pharmacological therapies, ... -
The Role of Mucin in the Toxicological Impact of Polystyrene Nanoparticles
(2018)The development of novel oral drug delivery systems is an expanding area of research and both new approaches for improving their efficacy and the investigation of their potential toxicological effect are crucial and should ... -
Surface-Modified Gold Nanoparticles Possessing Two-Channel Responsive Eu III /Tb III Cyclen Complexes as Luminescent Logic Gate Mimics
(2017)The development of material-supported molecular logic gate mimics (MGLMs) for contained application and device fabrication has become of increasing interest. Herein, we present the formation of ≈5 nm gold nanoparticles ...