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  • Family-based molecular genetic studies in bipolar affective disorder 

    Segurado, Ricardo (Trinity College (Dublin, Ireland). Department of Genetics, 2003)
    This thesis covers gene mapping experiments applied to bipolar affective disorder (BPD), a severe recurrent psychiatric condition with a lifetime prevalence of 1-2%, and a substantial familial component. The study sample ...
  • The SNP ratio test: pathway analysis of genome-wide association datasets 

    MORRIS, DEREK; HERON, ELIZABETH ANN; CORVIN, AIDEN PETER; GILL, MICHAEL; O'Dushlaine, Colm; Kenny, Elaine; Segurado, Ricardo (2009)
    Summary: We present a tool that assesses the enrichment of significant associations from genome-wide association studies (GWAS) in a pathway context. The SNP ratio test (SRT) compares the proportion of significant to ...