Browsing by Author "CORRIGAN, OWEN"
Now showing items 1-20 of 21
- Sort by:
- title
- issue date
- submit date
- Order:
- ascending
- descending
- Results:
- 5
- 10
- 20
- 40
- 60
- 80
- 100
-
Characterisation, solubility and intrinsic dissolution behaviour of benzamide:dibenzyl sulfoxide cocrystal
HEALY, ANNE; CORRIGAN, OWEN; TAJBER, LIDIA; GROSSJOHANN, CHRISTINE (2012)This study examined the 1:1 cocrystal benzamide:dibenzyl sulfoxide, comprising the poorly water soluble dibenzyl sulfoxide (DBSO) and the more soluble benzamide (BA), to establish if this cocrystal shows advantages in terms ... -
An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration.
CORRIGAN, OWEN (PLoS, 2011)BACKGROUND: The study aimed to investigate the pharmacokinetics of intravenous ciprofloxacin and the adequacy of 400 mg every 12 hours in critically ill Intensive Care Unit (ICU) patients on continuous veno-venous ... -
Exploring the assembly process and properties of novel crosslinker-free hyaluronate-based polyelectrolyte complex nanocarriers
TAJBER, LIDIA; SANTOS-MARTINEZ, MARIA; CORRIGAN, OWEN; UMERSKA, ANITA MONIKA; PALUCH, KRZYSZTOF; MEDINA MARTIN, CARLOS (2012) -
Impact of process variables on the micromeritic and physicochemical properties of spray dried microparticles - Part II. Physicochemical characterisation of spray dried materials
HEALY, ANNE; AMARO, MARIA INES; TAJBER, LIDIA; PALUCH, KRZYSZTOF; CORRIGAN, OWEN (2012) -
Impact of process variables on the micromeritic and physicochemical properties of spray dried porous microparticles - Part I. Introduction of a new Morphology Classification System
HEALY, ANNE; TAJBER, LIDIA; CORRIGAN, OWEN; PALUCH, KRZYSZTOF (2012) -
Intermolecular interactions between salmon calcitonin, hyaluronate, and chitosan and their impact on the process of formation and properties of peptide-loaded nanoparticles.
CORRIGAN, OWEN; TAJBER, LIDIA (2014)The principal aim of this work was to study the formulation of a ternary complex comprising salmon calcitonin (sCT), hyaluronate (HA), and chitosan (CS) in a nanoparticle (NP) format. As interactions between the constituents ... -
Investigating the effect of solubility and density gradients on local hydrodynamics and drug dissolution in the USP 4 dissolution apparatus
CORRIGAN, OWEN; LIU, BO; D'ARCY, DEIRDRE (2011)The aim of this investigation was to evaluate the effect of solubility and related solution density gradients, on hydrodynamics and dissolution rate in a low velocity pulsing flow, in the USP 4 flow-through dissolution ... -
Migrants, Welfare Systems and Social Citizenship in Ireland and Britain: Users or Abusers?
CORRIGAN, OWEN (Cambridge University Press, 2010)Public discourse on migrant interactions with state welfare systems has often assumed exploitative motivations on the part of migrants, with charges of welfare tourism a recurring theme among segments of the political ... -
Nanoparticles: pharmacological and toxicological significance
RADOMSKI, MAREK; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS; CORRIGAN, OWEN (2007) -
Optimisation of spray drying process conditions for sugar nanoporous microparticles (NPMPs) intended for inhalation
CORRIGAN, OWEN; HEALY, ANNE; TAJBER, LIDIA; AMARO, MARIA INES (2011)The present study investigated the effect of operating parameters of a laboratory spray dryer on powder characteristics, in order to optimise the production of trehalose and raffinose powders, intended to be used as carriers ... -
Particle engineering of materials for oral inhalation by dry powder inhalers. I - Particles of sugar excipients (trehalose and raffinose) for protein delivery
HEALY, ANNE; CORRIGAN, OWEN; TAJBER, LIDIA (2011)The pulmonary route of delivery offers a potential alternative to parenteral administration of peptides and proteins. Protection of protein structure is essential in both processing and storage of the final formulation. ... -
Particle engineering of materials for oral inhalation by dry powder inhalers. II - Sodium cromoglicate
HEALY, ANNE; CORRIGAN, OWEN; TAJBER, LIDIA (2011)Sodium cromoglicate is an antiasthmatic and antiallergenic drug used in inhalation therapy and commonly administered by a dry powder inhaler. In the present study we sought to examine the feasibility of producing nanoporous ... -
Preparation and characterisation of novel chlorothiazide potassium solid-state salt forms: intermolecular self assembly suprastructures
O'BRIEN, JOHN EUGENE; HEALY, ANNE MARIE; TAJBER, LIDIA; CORRIGAN, OWEN; MC CABE, THOMAS; PALUCH, KRZYSZTOF (Elsevier, 2011)Chlorothiazide (CTZ) is a poorly soluble diuretic agent. The aim of the present work was to produce and characterise a potassium salt form of chlorothiazide which has the potential advantages of improved aqueous solubility ... -
Preparation and solid state characterisation of chlorothiazide sodium intermolecular self assembly suprastructure
TAJBER, LIDIA; MC CABE, THOMAS; HEALY, ANNE MARIE; O'BRIEN, JOHN EUGENE; CORRIGAN, OWEN; PALUCH, KRZYSZTOF (Elsevier, 2010)Chlorothiazide (CTZ), unlike other thiazide diuretics, can form salts. An injectable formulation containing the sodium salt is available; however neither the physicochemical characteristics of the salt nor its solid state ... -
Self-assembled hyaluronate/protamine polyelectrolyte nanoplexes: synthesis, stability, biocompatibility and potential use as peptide carriers
TAJBER, LIDIA; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS; CORRIGAN, OWEN (2014)This work investigates a new type of polyelectrolyte complex nanocarrier composed of hyaluronic acid (HA) and protamine (PROT). Small (approximately 60 nm) and negatively charged nanoparticles (NPs) with a polydispersity ... -
Solid state characterisation of novel active pharmaceutical ingredients: co-crystal of a salbutamol hemiadipate salt with adipic acid (2:1:1) and salbutamol hemisuccinate salt
HEALY, ANNE MARIE; CORRIGAN, OWEN; TAJBER, LIDIA; PALUCH, KRZYSZTOF (Wiley, 2011)The production of salt or cocrystalline forms is a common approach to alter the physicochemical properties of pharmaceutical compounds. The goal of this work was to evaluate the impact of anion choice (succinate, adipate, ... -
Spray drying from organic solvents to prepare nanoporous/nanoparticulate microparticles (NPMPs) of protein:excipient composites designed for oral inhalation
HEALY, ANNE; TAJBER, LIDIA; CORRIGAN, OWEN (2012) -
A study of community pharmacy practice 1
Henman, Martin; CORRIGAN, OWEN (1991) -
A study of community pharmacy practice, 1: Pharmacists work patterns
CORRIGAN, OWEN; Henman, Martin (1991)