Browsing Administrative Staff Authors (Scholarly Publications) by Subject "Genes & Society"
Now showing items 1-4 of 4
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Characterising cytokine gene expression signatures in patients with severe sepsis
(2013)Introduction. Severe sepsis in humans may be related to an underlying profound immune suppressive state. We investigated the link between gene expression of immune regulatory cytokines and the range of illness severity in ... -
The prevalence of alpha-1 antitrypsin deficiency in Ireland
(2011)Background: Alpha-1 antitrypsin deficiency (AATD) results from mutations in the SERPINA1 gene and classically presents with early-onset emphysema and liver disease. The most common mutation presenting with clinical evidence ... -
A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up
(2003)BACKGROUND AND AIMS: Mutant tumour derived DNA has been detected in the sera of colorectal cancer patients. We investigated if mutant serum KRAS2 was detectable preoperatively in a large group of patients with colorectal ...