Browsing School of Pharmacy and Pharmaceutical Sciences by Subject "Bioprecursor"
Now showing items 1-2 of 2
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Part Two: Evaluation of N-methylbupropion as a Potential Bupropion Prodrug
(2014)N-methylbupropion was selected as a potential prodrug from our in vitro screening of analogues of bupropion described in the preceding paper. This study describes in vivo pharmacokinetics of N-methylbupropion in the ... -
Synthesis, screening and pharmacokinetic evaluation of potential prodrugs of bupropion
(2014)In general, prodrugs are developed to circumvent deficiencies associated with the absorption, distribution, metabolism, excretion or toxicological (ADMET) profile associated with the active drug. In our study, we select ...
