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Associations between Cardiovascular Signal Entropy and Cognitive Performance over Eight Years
(2021)
In this study, the relationship between non-invasively measured cardiovascular signal
entropy and global cognitive performance was explored in a sample of community-dwelling older
adults from The Irish Longitudinal Study ...
Improvement in cognitive impairment following a 12-week aerobic exercise intervention in individuals with non-cirrhotic chronic hepatitis C
(2020)
Cognitive impairment occurs in 30%-50% of patients with non-cirrhotic chronic hepatitis C virus (HCV) infection. Exercise is beneficial in preventing and treating cognitive impairment and cardiometabolic abnormalities in ...
Is phenotypical prefrailty all the same? A longitudinal investigation of two prefrailty subtypes in TILDA
(2019)
Background: Fried's frailty phenotype is defined by five criteria: exhaustion, unexplained weight loss, weakness, slowness and low physical activity. Prefrailty (PF) meets one or two criteria. PF is of interest as a target ...
The Importance of Age in the Prediction of Mortality by a Frailty Index: A Machine Learning Approach in the Irish Longitudinal Study on Ageing
(2021)
The quantification of biological age in humans is an important scientific endeavor in the face of ageing populations. The frailty index (FI) methodology is based on the accumulation of health deficits and captures variations ...
The use of an implantable loop recorder in the investigation of unexplained syncope in older people
(2003)
Introduction: Reveal is a patient activated implantable loop recorder device with an 18 month battery life now available to assist in the diagnosis of suspected syncope or arrhythmias. We present our experience using this ...
Should prevention of falls start earlier? Coordinated analyses of harmonised data on falls in middle-aged adults across four population-based cohort studies
(2018)
The prevalence of risk factors for falls increases during middle-age, but the prevalence of falls in this age-range is often overlooked and understudied. The aim was to calculate the prevalence of falls in middle-aged ...
EuGMS Task and Finish group on Fall-Risk-Increasing Drugs (FRIDs): Position on Knowledge Dissemination, Management, and Future Research
(2019)
Falls are a major public health concern in the older population, and certain medication classes are a significant risk factor for falls. However, knowledge is lacking among both physicians and older people, including ...
Tooth loss and cognitive decline in community dwelling older Irish adults: A cross-sectional cohort study
(2022)
Objectives: To investigate whether tooth loss and related loss of occluding tooth pairs, were associated with cognitive decline in a group of community dwelling older men and women from Ireland.
Methods: A group of 2508 ...
Differential Associations Between Two Markers of Probable Sarcopenia and Continuous Orthostatic Hemodynamics in The Irish Longitudinal Study on Ageing
(2022)
Background: Sarcopenia and orthostatic hypotension are growing age-related health burdens associated with adverse outcomes including falls. Despite a possible pathophysiological link, the association between the two disorders ...
NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease.
(2014)
This study is a European multicentre, randomised, double-blind, placebo-controlled trial investigating the efficacy and safety of nilvadipine as a disease course modifying treatment for mild-to-moderate Alzheimer's disease ...