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Complement regulator C4BP binds to Staphylococcus aureus surface proteins SdrE and Bbp inhibiting bacterial opsonization and killing.
(2013)
Staphylococcus aureus is a premier human pathogen and the most common cause of osteoarticular, wound, and implanted device infections. We recently demonstrated S. aureus efficiently binds the classical complement regulator ...
Telomeric ORFs (TLOs) in Candida spp. Encode mediator subunits that regulate distinct virulence traits.
(2014)
The
TLO
genes are a family of telomere-associated ORFs in the fungal pathogens
Candida albicans
and
C. dubliniensis
that
encode a subunit of the Mediator complex with homology to Med2. The more virulent pathogen
C. ...
Protein A Is Released into the Staphylococcus aureus Culture Supernatant with an Unprocessed Sorting Signal.
(2015)
The immunoglobulin binding protein A (SpA) of Staphylococcus aureus is synthesized as a precursor with a C-terminal sorting signal. The sortase A enzyme mediates covalent attachment to peptidoglycan so that SpA is displayed ...
A single amino acid in the HA of pH1N1 2009 influenza virus affects cell tropism in human airway epithelium, but not transmission in ferrets.
(2011)
he first pandemic of the 21
st
century, pandemic H1N1 2009 (pH1N1 2009), emerged from a swine-origin source. Although
human infections with swine-origin influenza have been reported previously, none went on to cause a ...