Browsing by Subject "chemokine"
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Addition of a Viral Immunomodulatory Domain to Etanercept Generates a Bifunctional Chemokine and TNF Inhibitor
(2020)The inhibition of tumor necrosis factor (TNF) through the use of either antibodies or soluble receptors is a highly effective strategy for the clinical control of chronic inflammatory conditions such as rheumatoid arthritis. ... -
A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1beta, TNF-alpha and IL-6 Challenges in C57BL/6 Mice.
(2013)It is increasingly clear that systemic inflammation has both adaptive and deleterious effects on the brain. However, detailed comparisons of brain effects of systemic challenges with different pro-inflammatory cytokines ...