Browsing by Subject "LUNG CANCER"
Now showing items 1-7 of 7
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Clinicoradiological outcomes after radical radiotherapy for lung cancer in patients with interstitial lung disease.
(2023)Objective: Interstitial lung disease (ILD) is relatively common in patients with lung cancer with an incidence of 7.5%. Historically pre-existing ILD was a contraindication to radical radiotherapy owing to increased radiation ... -
Extracellular vesicles report on the MET status of their cells of origin regardless of the method used for their isolation.
(2020)MET pathway is an important actionable target across many solid tumour types and several MET inhibitors have been developed. Extracellular vesicles (EVs) are proposed to be mini-maps of their cells of origin. However, the ... -
p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis.
(2019)SESTRINs (SESN1-3) are proteins encoded by an evolutionarily conserved gene family that plays an important role in the regulation of cell viability and metabolism in response to stress. Many of the effects of SESTRINs are ... -
Sestrin-2 is significantly increased in malignant pleural effusions due to lung cancer and is potentially secreted by pleural mesothelial cells.
(2016)Objectives: Sestrin-2 (Sesn2) belongs to a family of highly conserved antioxidant proteins that were discovered as p53-inducible proteins and inhibits cell growth and proliferation. Our aim was to assess the levels of Sesn2 ... -
Study of Natural Radioactivity Levels and Radon/Thoron Release Potential of Bedrock and Soil in Southeastern Ireland
(2021)Radon (222Rn) and thoron (220Rn) account for almost two-thirds of the annual average radiation dose received by the Irish population. A detailed study of natural radioactivity levels and radon and thoron exhalation rates ... -
Utilization of radiometric data for mapping primary and secondary sources of gamma radiation and radon/thoron release potentials in Ireland
(2024)Background: This paper presents a novel approach to predict and map radon and thoron levels. We developed separate radon and thoron prediction maps for Ireland and introduced a system for producing high-resolution 3D ...
