Browsing by Subject "Candida albicans"
Now showing items 1-20 of 25
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Alcohol consumption modulates Candida albicans-induced oral carcinogenesis and progression
(2023)Objectives: This study aimed to determine the impact of low levels of alcohol consumption on the interaction of the oral cavity with Candida albicans, a species that is commonly found at higher levels in the oral cavities ... -
The Candida albicans-Specific Gene EED1 Encodes a Key Regulator of Hyphal Extension
(2011)The extension of germ tubes into elongated hyphae by Candida albicans is essential for damage of host cells. The C. albicans-specific gene EED1 plays a crucial role in this extension and maintenance of filamentous growth. ... -
Characterisation of Staphylococcal and Candida Populations from Healthy and Diseased Oral and Subgingival Sites Reveals a High Prevalence and Diversity of the Arginine Catabolic Mobile Element ACME in Staphylococcus epidermidis
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2018)The oral cavity harbours a diverse microbiological population, that exists mainly as plaque biofilm, the accumulation of which is associated with oral diseases such as periodontal disease and peri-implantitis. Traditionally, ... -
COMPARATIVE ADHERENCE OF CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS TO HUMAN BUCCAL EPITHELIAL CELLS AND EXTRACELLULAR MATRIX PROTEINS
(2014)Candida albicans and Candida dubliniensis are very closely related pathogenic yeast species. Despite their close relationship, the former is a far more successful coloniser and pathogen of humans. The purpose of the current ... -
COMPARATIVE GENOMICS USING CANDIDA ALBICANS DNA MICROARRAYS REVEALS ABSENCE AND DIVERGENCE OF VIRULENCE ASSOCIATED GENES IN CANDIDA DUBLINIENSIS
(2004)Candida dubliniensis is a pathogenic yeast species closely related to Candida albicans. However, it is less frequently associated with human disease and displays reduced virulence in animal models of infection. We have ... -
COMPARATIVE TRANSCRIPT PROFILING OF Candida albicans AND Candida dubliniensis IDENTIFIES SFL2, A C. albicans GENE REQUIRED FOR VIRULENCE IN A RECONSTITUTED EPITHELIAL INFECTION MODEL
(2010)Candida albicans and Candida dubliniensis are closely related species displaying differences in virulence and genome content, therefore providing potential opportunities to identify novel C. albicans virulence genes. C. ... -
Differential filamentation of Candida albicans and C. dubliniensis is governed by nutrient regulation of UME6 expression
(2010)Candida dubliniensis is closely related to C. albicans, however it is responsible for fewer infections in humans and is less virulent in animal models of infection. C. dubliniensis forms fewer hyphae in vivo and this may ... -
DIFFERENTIAL FILAMENTATION OF CANDIDA ALBICANS AND C. DUBLINIENSIS IS GOVERNED BY NUTRIENT REGULATION OF UME6 EXPRESSION
(2010)Candida dubliniensis is closely related to Candida albicans; however, it is responsible for fewer infections in humans and is less virulent in animal models of infection. C. dubliniensis forms fewer hyphae in vivo, and ... -
DIFFERENTIAL REGULATION OF THE TRANSCRIPTIONAL REPRESSOR NRG1 ACCOUNTS FOR ALTERED HOST CELL INTERACTIONS IN CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS
(2007)Candida dubliniensis is genetically closely related to C. albicans, but causes fewer infections in humans and exhibits reduced virulence and filamentation in animal models of infection. We investigated the role of the ... -
DIFFERENTIAL VIRULENCE OF CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS: A ROLE FOR TOR KINASE?
(2011)Candida albicans and Candida dubliniensis are two very closely related species of pathogenic yeast. C. albicans is the most prevalent species in the human gastrointestinal tract and is responsible for far more opportunistic ... -
EFFECTIVE CLEANING AND DECONTAMINATION OF THE INTERNAL AIR AND WATER CHANNELS, HEADS AND HEAD-GEARS OF MULTIPLE CONTRA ANGLE DENTAL HANDPIECES USING AN ENZYMATIC DETERGENT AND AUTOMATED WASHER DISINFECTION IN A DENTAL HOSPITAL SETTING
(2022)Background Dental handpieces (DHPs) are reusable invasive medical devices that must be cleaned, decontaminated, lubricated and steam sterilized after use. DHPs have a complex internal design including narrow channels, ... -
ENRICHMENT OF MULTILOCUS SEQUENCE TYPING CLADE 1 WITH ORAL CANDIDA ALBICANS ISOLATES IN PATIENTS WITH UNTREATED PERIODONTITIS
(2012)This study investigated the prevalence and cell density of Candida species in periodontal pockets, healthy subgingival sites and in oral rinses of patients with untreated periodontitis. Twenty-one periodontitis patients ... -
The function of the TLO gene family of Candida albicans
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2022)Candida albicans is the most common cause of Candida infection worldwide. It is more pathogenic than all the other members of the genus, and it is thought that expansion of several key gene families accounts for this ... -
Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress
(Wiley-Blackwell, 2009)Candida albicans is more pathogenic than Candida dubliniensis. However, this disparity in virulence is surprising given the high level of sequence conservation and the wide range of phenotypic traits shared by these two ... -
GENOTYPING Candida albicans FROM CANDIDA LEUKOPLAKIA AND NON-CANDIDA LEUKOPLAKIA SHOWS NO ENRICHMENT OF MULTILOCUS SEQUENCE TYPING CLADES BUT ENRICHMENT OF ABC GENOTYPE C IN CANDIDA LEUKOPLAKIA
(2013)Oral leukoplakias are histopathologically-diagnosed as Candida leukoplakia or non-Candida leukoplakia by the presence or absence of hyphae in the superficial epithelium. Candida leukoplakia lesions have significantly ... -
Global Transcriptome Sequencing Identifies Chlamydospore Specific Markers in Candida albicans and Candida dubliniensis.
(2013)Candida albicans and Candida dubliniensis are pathogenic fungi that are highly related but differ in virulence and in some phenotypic traits. During in vitro growth on certain nutrient-poor media, C. albicans and C. ... -
Lower filamentation rates of Candida dubliniensis contribute to its lower virulence in comparison with Candida albicans
(Elsevier, 2007)Candida albicans and Candida dubliniensis are very closely related yeast species. In this study, we have conducted a thorough comparison of the ability of the two species to produce hyphae and their virulence in two ... -
MOLECULAR EPIDEMIOLOGY. PHYLOGENY AND EVOLUTION OF Candida albicans
(2014)A small number of Candida species form part of the normal microbial flora of mucosal surfaces in humans and may give rise to opportunistic infections when host defences are impaired. Candida albicans is by far the most ... -
Purification and germination of Candida albicans and Candida dubliniensis chlamydospores cultured in liquid media
(2009-06-30)Candida albicans and Candida dubliniensis are the only Candida species that have been observed to produce chlamydospores. The function of these large, thick-walled cells is currently unknown. In this report we describe ... -
Telomeric ORFs (TLOs) in Candida spp. encode Mediator subunits that regulate distinct virulence traits
(2014)The TLO genes are a family of telomere-associated ORFs in the fungal pathogens Candida albicans and C. dubliniensis that encode a subunit of the Mediator complex with homology to Med2. The more virulent pathogen C. albicans ...
