Browsing by Subject "Ageing"
Now showing items 1-20 of 781
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2012 - That was the year that was
(2013)Geriatric medicine has an encyclopaedic sweep, reflecting the complexity of both the ageing process and of our patient group. Keeping up with, and making sense of, the relevant scientific literature is challenging, especially ... -
24-hour ambulatory electrocardiographic monitoring is unhelpful in the investigation of older persons with recurrent falls
(2005)Background: although frequently used in the assessment of patients with falls, it is unclear whether 24-hour ambulatory electrocardiography contributes to their assessment in older persons. Objective: to ... -
5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice
(2018)In vertebrates, the initial step in heme biosynthesis is the production of 5-aminolevulinic acid (ALA) by ALA synthase (ALAS). ALA formation is believed to be the rate-limiting step for cellular heme production. Recently, ... -
α-TLR2 antibody attenuates the Aβ-mediated inflammatory response in microglia through enhanced expression of SIGIRR.
(2015)The immunoregulatory function of single-Ig-interleukin-1 related receptor (SIGIRR) is derived from its ability to constrain the inflammatory consequences of interleukin (IL)-1R and toll-like receptor (TLR)4 activation. ... -
ACE gene I/D polymorphism and severity of SARS-CoV-2 infection in hospitalized patients: a metanalysis
(2021)Background Hypertension and type 2 diabetes increase the risk of severe SARS-CoV-2 infection. On the other hand, homozygous ACE deletion polymorphism (DD) has been associated with these two diseases and risk of acute ... -
Acute hospital staff s attitudes towards dementia and perceived dementia knowledge: a cross-sectional survey in Ireland
(2020)Background: Little is known about staff’s attitudes in Irish acute hospital settings towards people living with dementia and their perceived dementia knowledge. The aim of this study was to understand the general level of ... -
Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium
(2020)Systemic infection triggers a spectrum of metabolic and behavioral changes, collectively termed sickness behavior, which while adaptive, can affect mood and cognition. In vulnerable individuals, acute illness can also ... -
Adapting prescribing criteria for amyloid-targeted antibodies for adults with Down syndrome
(2024)Prior authorization criteria for Federal Drug Administration (FDA) approved immunotherapeutics, among the class of anti-amyloid monoclonal antibodies (mAbs), established by state drug formulary committees, are tailored for ... -
Adapting prescribing criteria for amyloid-targeted antibodies for adults with Down syndrome
(2024)Prior authorization criteria for Federal Drug Administration (FDA) approved immunotherapeutics, among the class of anti-amyloid monoclonal antibodies (mAbs), established by state drug formulary committees, are tailored ... -
Addressing Ethical Issues in the Design of Patient & Caregiver Monitoring Technology in Aged Care Settings
(Nova Publishers, 2020)The monitoring and evaluation of patient health and wellbeing, along with the quality of care delivery is critical to patient safety. The aged care sector has faced many scandals about the quality of aged care services. ... -
Addressing Medication Management Challenges for Older People with Multimorbidities: A Multi-Stakeholder Approach
(ACM, 2017)Multimorbidity, the presence of two or more chronic conditions, places a significant burden on health systems globally. People managing multiple chronic conditions face burdensome and complex treatment plans. Polypharmacy, the ... -
ADELE: Evaluating and Benchmarking an Artificial Conversational Care Agent
(http://casforhealth.org, 2020-04-26)This paper provides an overview of a planned experiment to evaluate the latest iteration of ADELE, an artificial conversational agent to aid in the care of the elderly. It is being evaluated against an earlier iteration ... -
Admissions for Orthostatic Hypotension: an Analysis of NHS England Hospital Episode Statistics Data
(2019)Objectives To determine whether admissions for orthostatic hypotension (OH) and its consequences, such as falls, have changed over the past 10 years in the National Health Service (NHS) England. Setting Data from NHS ... -
Adolescents perception of the COVID-19 pandemic restrictions and associated mental health and well-being: gender, age and socioeconomic differences in 22 countries
(2024)Background: The COVID-19-pandemic has had a profound impact on the lives of adolescents worldwide. This study examined the subjective perception of the COVID-19 pandemic measures and its association with mental health and ... -
Advanced Assistive Technologies for Elderly People: A Psychological Perspective on Seniors' Needs and Preferences (part A)
(2020)This paper provides an overview of the literature concerning Seniors’ psychological perspective in exploiting assistive robots and the embodied conversational agents. The main theoretical models devoted to assess user’s ... -
Advanced Assistive Technologies for Elderly People: A Psychological Perspective on Seniors' Needs and Preferences (part B)
(2021)This paper provides a general overview of the literature regarding advanced assistive technologies devoted to improving elders’ life. Recent studies on assistive robots and embodied conversational agents ... -
Advancing a Human Factors & Ethics Canvas for New Driver Assistance Technologies Targeted at Older Adults
(Springer, Cham, 2020)Automated driving solutions represent a potential solution to promoting driver persistence and the management of fitness to drive issues in older adults. This paper reports on the application of a ‘Human Factors & Ethics ...
