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dc.contributor.authorMonaghan, Michael
dc.contributor.authorOlvera, Dinorath
dc.contributor.authorSohrabi, Mina
dc.contributor.authorHendy, Gillian
dc.date.accessioned2020-03-03T15:05:52Z
dc.date.available2020-03-03T15:05:52Z
dc.date.issued2020
dc.date.submitted2020en
dc.identifier.citationOlvera, D., Sohrabi, M., Hendy, G. & Monaghan, M.G., Electroconductive Melt Electrowritten Patches Matching the Mechanical Anisotropy of Human Myocardium, Advanced Functional Materials, 2020en
dc.identifier.issn16163028 1616301X
dc.identifier.otherY
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201909880
dc.identifier.urihttp://hdl.handle.net/2262/91680
dc.descriptionPUBLISHEDen
dc.description.abstractCardiac patches represent a promising strategy for the treatment of myocardial infarction (MI). Here, an electroconductive cardiac patch that conforms to the mechanics of human myocardium is fabricated. By melt electrospinning writing (MEW), it is possible to fabricate an auxetic patch that can overcome the limited range of elasticity seen in conventional square patch designs. The auxetic patches can accommodate the strains and stresses exhibited by the human myocardium during diastole and systole. It is shown that the geometry of the auxetic patches can be fine‐tuned to reflect anisotropic mechanical properties. The anisotropic ratio of effective stiffness (E1/E2) of the auxetic patches agrees with the directionally‐dependent mechanics of the heart. Furthermore, in situ polymerization of doped‐polypyrrole (PPy) on the auxetic patches confers electroconductive properties close to those reported of human myocardium. This approach demonstrates the potential use of a rational design of PPy‐coated patches for their use as cardiac patches.en
dc.language.isoenen
dc.relation.ispartofseriesAdvanced Functional Materials;
dc.rightsYen
dc.subjectCardiac patchesen
dc.subjectMelt electrospinning writingen
dc.subjectAuxetic materialsen
dc.subjectMechanical anisotropyen
dc.subjectElectroconductive materialsen
dc.titleElectroconductive Melt Electrowritten Patches Matching the Mechanical Anisotropy of Human Myocardiumen
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/monaghmi
dc.identifier.rssinternalid213221
dc.identifier.doihttp://dx.doi.org/10.1002/adfm.201909880
dc.rights.ecaccessrightsopenAccess
dc.identifier.orcid_id0000-0002-5530-4998


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