Trypanotolerace in West African cattle and the population genetic effects of selection

Abstract

A panel of 69 microsatellite loci was used to investigate the population genetic effects of selection at genes on linked, neutral markers. Loci were typed in African and European Bos taurus cattle and Bos indicus populations from the Indian subcontinent. Where data was already available, this was added to the dataset. The microsatellites included five loci within 3cM of the bovine class IIa MHC region on chromosome 23, eight loci each within a few kilobases of known genes, and 56 anonymous loci not known to be linked to genes. A range of genetic analyses were performed on the data.