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dc.contributor.advisorGilmer, John
dc.contributor.authorLally, Maeve
dc.date.accessioned2019-07-25T13:35:29Z
dc.date.available2019-07-25T13:35:29Z
dc.date.issued2003
dc.identifier.citationMaeve Lally, 'Studies into the in vitro metabolism and antiplatelet effects of novel aspirin ester prodrugs', [thesis], Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2003, pp 309
dc.identifier.otherTHESIS 6740
dc.identifier.urihttp://hdl.handle.net/2262/88918
dc.description.abstractAspirin is the most commonly used antiplatelet agent in the world, and is invaluable in prevention o f myocardial infarction, thrombosis and stroke. However prolonged use has been associated with gastrointestinal side-effects such as ulceration and haemorrhage which may be fatal. This thesis describes the design and evaluation of aspirin prodrugs, which may liberate aspirin only on reaching the circulation, thus circumventing the GIT and having a potentially less severe gastrotoxicity profile.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12403823
dc.subjectPharmaceutical Chemistry, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleStudies into the in vitro metabolism and antiplatelet effects of novel aspirin ester prodrugs
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 309
dc.description.noteTARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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