The impact of neuronal activity manipulations on recovery after complete spinal transection in the Eel

Abstract

Spinal cord injury is a tragically debilitating event affecting up to 5 or more out of every 100,000 people in many countries across the globe. Axotomised neurons in the mammalian CNS are unfortunately unable to regenerate properly after such injury, unlike those in lower vertebrates such as fish, which are readily repaired throughout life.