Ischaemia-reperfusion-induced renal injury : pathogenesis & modulation implications for transplantation
Citation:
Karen Stokes, 'Ischaemia-reperfusion-induced renal injury : pathogenesis & modulation implications for transplantation', [thesis], Trinity College (Dublin, Ireland). Department of Physiology, 2004, pp 409Abstract:
Ischaemia-reperfusion is unavoidable during transplantation, but may promote allograft
rejection. Preconditioning with a sub-lethal stress protects cells against a subsequent
otherwise lethal stress, possibly through the induction of heat shock proteins. This thesis
establishes a rat model of renal ischaemia-reperfusion injury and assesses the protective
capability of several preconditioning methods. The most effective method was used to
evaluate antigen expression and long-term protection.
Author: Stokes, Karen
Advisor:
Kelly, CathalBell, Christopher
Qualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). Department of PhysiologyNote:
TARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ieType of material:
thesisAvailability:
Full text availableKeywords:
Physiology, Ph.D., Ph.D. Trinity College DublinMetadata
Show full item recordLicences: