Browsing Genetics by Sponsor "Irish Cancer Society"
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A new family of vertebrate-specific Polycombs encoded by the Lcor/Lcorl genes balance PRC2 subtype activities
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)The Polycomb Repressive Complex 2 (PRC2) is composed of the core subunits SUZ12, EED, RBBP4/7 and EZH1/2, which together are responsible for all di- and tri- methylation of lysine 27 on Histone H3 (H3K27me2/3). In addition, ...
