Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

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Journal Article

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2018

Author:

CORVIN, AIDEN

DONOHOE, GARY

GILL, MICHAEL

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Davies, G. and Lam, M. and Harris, S.E. and Trampush, J.W. and Luciano, M. and Hill, W.D. and Hagenaars, S.P. and Ritchie, S.J. and Marioni, R.E. and Fawns-Ritchie, C. and Liewald, D.C.M. and Okely, J.A. and Ahola-Olli, A.V. and Barnes, C.L.K. and Bertram, L. and Bis, J.C. and Burdick, K.E. and Christoforou, A. and Derosse, P. and Djurovic, S. and Espeseth, T. and Giakoumaki, S. and Giddaluru, S. and Gustavson, D.E. and Hayward, C. and Hofer, E. and Ikram, M.A. and Karlsson, R. and Knowles, E. and Lahti, J. and Leber, M. and Li, S. and Mather, K.A. and Melle, I. and Morris, D. and Oldmeadow, C. and Palviainen, T. and Payton, A. and Pazoki, R. and Petrovic, K. and Reynolds, C.A. and Sargurupremraj, M. and Scholz, M. and Smith, J.A. and Smith, A.V. and Terzikhan, N. and Thalamuthu, A. and Trompet, S. and Van Der Lee, S.J. and Ware, E.B. and Windham, B.G. and Wright, M.J. and Yang, J. and Yu, J. and Ames, D. and Amin, N. and Amouyel, P. and Andreassen, O.A. and Armstrong, N.J. and Assareh, A.A. and Attia, J.R. and Attix, D. and Avramopoulos, D. and Bennett, D.A. and Böhmer, A.C. and Boyle, P.A. and Brodaty, H. and Campbell, H. and Cannon, T.D. and Cirulli, E.T. and Congdon, E. and Conley, E.D. and Corley, J. and Cox, S.R. and Dale, A.M. and Dehghan, A. and Dick, D. and Dickinson, D. and Eriksson, J.G. and Evangelou, E. and Faul, J.D. and Ford, I. and Freimer, N.A. and Gao, H. and Giegling, I. and Gillespie, N.A. and Gordon, S.D. and Gottesman, R.F. and Griswold, M.E. and Gudnason, V. and Harris, T.B. and Hartmann, A.M. and Hatzimanolis, A. and Heiss, G. and Holliday, E.G. and Joshi, P.K. and Kÿhönen, M. and Kardia, S.L.R. and Karlsson, I. and Kleineidam, L. and Knopman, D.S. and Kochan, N.A. and Konte, B. and Kwok, J.B. and Le Hellard, S. and Lee, T. and Lehtimÿki, T. and Li, S.-C. and Liu, T. and Koini, M. and London, E. and Longstreth, W.T. and Lopez, O.L. and Loukola, A. and Luck, T. and Lundervold, A.J. and Lundquist, A. and Lyytikÿinen, L.-P. and Martin, N.G. and Montgomery, G.W. and Murray, A.D. and Need, A.C. and Noordam, R. and Nyberg, L. and Ollier, W. and Papenberg, G. and Pattie, A. and Polasek, O. and Poldrack, R.A. and Psaty, B.M. and Reppermund, S. and Riedel-Heller, S.G. and Rose, R.J. and Rotter, J.I. and Roussos, P. and Rovio, S.P. and Saba, Y. and Sabb, F.W. and Sachdev, P.S. and Satizabal, C.L. and Schmid, M. and Scott, R.J. and Scult, M.A. and Simino, J. and Slagboom, P.E. and Smyrnis, N. and Soumaré, A. and Stefanis, N.C. and Stott, D.J. and Straub, R.E. and Sundet, K. and Taylor, A.M. and Taylor, K.D. and Tzoulaki, I. and Tzourio, C. and Uitterlinden, A. and Vitart, V. and Voineskos, A.N. and Kaprio, J. and Wagner, M. and Wagner, H. and Weinhold, L. and Wen, K.H. and Widen, E. and Yang, Q. and Zhao, W. and Adams, H.H.H. and Arking, D.E. and Bilder, R.M. and Bitsios, P. and Boerwinkle, E. and Chiba-Falek, O. and Corvin, A. and De Jager, P.L. and Debette, S. and Donohoe, G. and Elliott, P. and Fitzpatrick, A.L. and Gill, M. and Glahn, D.C. and Hÿgg, S. and Hansell, N.K. and Hariri, A.R. and Ikram, M.K. and Jukema, J.W. and Vuoksimaa, E. and Keller, M.C. and Kremen, W.S. and Launer, L. and Lindenberger, U. and Palotie, A. and Pedersen, N.L. and Pendleton, N. and Porteous, D.J. and Rÿikkönen, K. and Raitakari, O.T. and Ramirez, A. and Reinvang, I. and Rudan, I. and Rujescu, D. and Schmidt, R. and Schmidt, H. and Schofield, P.W. and Schofield, P.R. and Starr, J.M. and Steen, V.M. and Trollor, J.N. and Turner, S.T. and Van Duijn, C.M. and Vill, Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function, Nature Communications, 9, 1, 2018, 2098-

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Author: CORVIN, AIDEN; DONOHOE, GARY; GILL, MICHAEL

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http://hdl.handle.net/2262/83228

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Nature Communications
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http://dx.doi.org/10.1038/s41467-018-04362-x

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