The effects of depression and electroconvulsive therapy on retrospective memory and general cognition : a longitudinal study

Abstract

The objectives of this work were to investigate the effects of depression on retrospective memory, in addition to attention, psychomotor and executive function, in depressed patients receiving pharmacotherapy treatment compared to heahhy controls (The Mem-Dep Study). The second objective was to examine retrograde memory function in patients in a randomised controlled non-inferiority trial investigating the effectiveness and side-effects of high-dose Right Unilateral (RUL) ECT and standard Bitemporal (BT) ECT in severe depression (EFFECT-Dep Trial).