Browsing Mechanical, Manufacturing & Biomedical Eng by Title
Now showing items 679-698 of 903
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Potential for combined delivery of riboflavin and all-trans retinoic acid, from silk fibroin for corneal bioengineering.
(2019)Millions of people worldwide suffer from vision impairing conditions resulting from corneal injury or disease. Silk fibroin (SF) is an emerging biopolymer that has been used for several applications including the fabrication ... -
Powder stream characteristics in cold spray nozzles
(2011)The exponential increase of industrial demand in the past two decades has led scientists to the development of alternative technologies for the fast manufacturing of engineering components, aside from ... -
Power and position-oriented process monitoring of freeform abrasive machining
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2013)Abrasive machining is used for the generation of freeform femoral implant surfaces in the biomedical industry. The abrasive machining operation is typified by high speed material removal in multiple axes, difficult-to-machine ... -
A practical approach to parameter identification for a lightly damped, weakly nonlinear system
(Elsevier, 2008)Fluidelastic systems are often lightly damped and exhibit weak non-linear damping. The weak linear and non-linear damping forces have a significant effect on the long term behaviour of the system. However, parameter ... -
PRACTICAL CONSIDERATIONS FOR THE DESIGN OF AUTONOMOUS MOBILE ROBOTS
(2012)This paper addresses the practical challenges that engineers encounter when designing autonomous mobile robots. The issues faced are multi -disciplinary in nature and become exponentially more co mplex as the ... -
Preclinical to clinical translation for intervertebral disc repair: Effects of species-specific scale, metabolism, and matrix synthesis rates on cell-based regeneration
(2023)Background: A significant hurdle for potential cell-based therapies is the subsequent survival and regenerative capacity of implanted cells. While many exciting developments have demonstrated promise preclinically, cell-based ... -
Prediciton of fatigue failure in engineering components using the finite element method
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2000)Prediction of fatigue failure in engineering artefects is becoming increasingly important as we enter the third millennium; more catastrophic fatigue failures will occur as engineers push the limits of design even further ... -
PREDICTION OF ENGINEERING STUDENT PROGRESSION FROM ENTRANCE DATA
(2012)Most Western economies are suffering from problems in attracting students to study Science, Engineering and T echnology courses at university level. Concurrently, engineering programmes te nd to have higher dropout ... -
Prediction of optimal mechanical properties for a scaffold used in osteochondral defect repair
(Mary Ann Liebert, 2006)The optimal mechanical properties of a scaffold to promote cartilage generation in osteochondral defects in vivo are not known. During normal daily activities cartilage is subjected to large cyclic loads that not only ... -
Predictions of Rotor Broadband Noise
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2018)This thesis presents an enhanced method for predicting aerodynamically generated broadband noise, produced by rotating machinery. The method improves on existing work for Vertical Axis Wind Turbine (VAWT) noise prediction, ... -
The predictive capacity of the MADYMO ellipsoid pedestrian model for pedestrian ground contact kinematics and injury evaluation
(2021)Pedestrian injuries occur in both the primary vehicle contact and the subsequent ground contact. Currently, no ground contact countermeasures have been implemented and no pedestrian model has been validated for ground ... -
Predictive capacity of the MADYMO Multibody human body model applied to head kinematics during rugby union tackles
(MDPI - Applied Sciences, 2019)Multibody models have not yet been evaluated for reconstructing head kinematics during sports impacts. Accordingly, the goal of this study was to utilise whole-body motion data from twenty upper and mid/lower trunk rugby ... -
A pressure-based estimate of synthetic jet velocity
(2007)Synthetic jets are used for active flow control and enhanced heat transfer, and are typically generated by an orifice connected to a cavity with movable diaphragm actuator. Low-power operation is achieved by matching ... -
Pressure-induced mesenchymal stem cell osteogenesis is dependent on intermediate filament remodeling.
(2019)Macroscale loading of bone generates a complex local mechanical microenvironment that drives osteogenesis and bone mechanoadaptation. One such mechanical stimulus generated is hydrostatic pressure (HP); however, the effect ... -
Primary cilium-mediated MSC mechanotransduction is dependent on Gpr161 regulation of hedgehog signalling.
(2021)The benefits of physical loading to skeletal mass are well known. The primary cilium has emerged as an important organelle in bone mechanobiology/mechanotransduction, particularly in mesenchymal stem/stromal cells, yet the ... -
Priming as a strategy to overcome detrimental pH effects on cells for intervertebral disc regeneration.
(2021)Disc disease is characterised by degeneration of the nucleus pulposus (NP), the central gelatinous tissue of the intervertebral disc (IVD). As degeneration progresses, the microenvironment of the IVD becomes more hostile ... -
Process, precedent, and community : new learning environments for engineering design
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2014)Project-based design courses are an increasingly conunon component of engineering education. Most engineering schools have traditionally emphasized the analytical and scientific aspects of the discipline, and an increase ... -
Promoting endogenous articular cartilage regeneration using extracellular matrix scaffolds
(2022)Articular cartilage defects fail to heal spontaneously, typically progressing to osteoarthritis. Bone marrow stimulation techniques such as microfracture (MFX) are the current surgical standard of care; however MFX typically ...
