Browsing Mechanical, Manufacturing & Biomedical Eng by Title
Now showing items 232-251 of 908
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The Development of a Novel 3D Bioprinting Strategy to Drive Vascularisation, and its Application for Bone Tissue Engineering
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)One of the major challenges facing the field of tissue engineering today is vascularisation. Without a system in place to circulate oxygen, nutrients and metabolites, the size of many tissue engineered constructs is ... -
Development of a novel powder sheets printing process towards the next generation of additive manufacturing: the role of laser defocusing
(2024)To address safety and labour-intensive challenges in laser powder bed fusion, a novel Metal Additive Manufacturing using Powder Sheets (MAPS) method is employed. By examining the formation mechanism of the melt pool, we ... -
Development of a performance framework to support the innovation process
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Performance frameworks (PFs) for measuring the innovation process are critical for both research and practice. However, existing PFs neglect performance indicators (PIs) and dimensions relevant to companies' current ... -
DEVELOPMENT OF AN AUTONOMOUS ROBOTIC HAND WITH HUMAN INTERACTION CAPABILITIES
(2012)A multiple degree-of-freedom hand has been developed which can interact with a human on a fundamental level. Th e robotic hand is closely modelled on a human hand, consisting of four fingers a nd a thumb. The digits ... -
Development of an off-the-shelf biomimetic vascular graft for small diameter vascular regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2023)Cardiovascular disease is one of the leading causes of death worldwide. The impairment of blood flow can require a total vessel substitution, but current grafts fail to recapitulate the unique mechanical behavior of native ... -
The development of biomimetic scaffolds for osteochondral tissue engineering
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)Articular cartilage (AC) is a soft tissue lining the ends of the bones in our joints. Even minor lesions in AC cause pain, impaired mobility and can develop to osteoarthritis (OA), a disease affecting millions of adults ... -
Development of localised process parameter control for repeatability in metal additive manufacturing
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)Due to the many advantages associated with metal additive manufacturing (AM) processes, research into these technologies has grown significantly over recent years. However, repeatability and reproducibility are critical ... -
Development of mechanobiomimetic strategies to drive stem cell behaviour for bone regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)There are a host of cases where clinical intervention must be taken to treat diseased or damaged bone, including severe fractures, defects, tumours requiring tissue removal, and debilitating diseases such as osteoporosis. ... -
Development, modelling and characterization of metal micro-textured thermal interface materials
(Trinity College (Dublin, Ireland). Department of Mechanical and Manufacturing Engineering, 2010)A metal micro-textured thermal interface material (MMT-TIM) has been developed to address the shortcomings of conventional TIMs. In the present study, the MMT-TEVIs consist of silver foils with raised, small-scale, hollow ... -
A Developmental Engineering-Based Approach to Bone Repair: Endochondral Priming Enhances Vascularization and New Bone Formation in a Critical Size Defect
(2020)There is a distinct clinical need for new therapies that provide an effective treatment for large bone defect repair. Herein we describe a developmental approach, whereby constructs are primed to mimic certain aspects of ... -
Dextran Preserves Native Corneal Structure During Decellularization.
(2016)Corneal decellularization has become an increasingly popular technique for generating scaffolds for corneal regeneration. Most decellularization procedures result in tissue swelling, thus limiting their application. Here, ... -
Diffusion tensor imaging and arterial tissue: establishing the influence of arterial tissue microstructure on fractional anisotropy, mean diffusivity and tractography
(2021)In this study we investigated the potential of diffusion tensor imaging (DTI) for providing insight into microstructural changes in arterial tissue by exploring the influence that cell, collagen and elastin content have ... -
Digital image correlation and finite element modelling as a method to determine mechanical properties of human soft tissue in vivo.
(2009)The mechanical properties of human soft tissue are crucial for impact biomechanics, rehabilitation engineering and surgical simulation. Validation of these constitutive models using human data remains challenging and often ... -
Direct mechanical characterization of prostate tissue-a systematic review.
(2018)Background Direct mechanical characterisation of tissue is the application of engineering techniques to biological tissue to ascertain stiffness or elasticity, which can change in response to disease states. A number of ... -
Directional Solidification Experiments with the Transparent Model Alloy Neopentyl Glycol-35wt.%(D)Camphor
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)This thesis describes the development of an experimental facility in combination with image processing and computer vision techniques for the visualisation and characterisation of dendritic growth structures in the transparent ... -
Does ball carrier technique influence tackler head injury assessment risk in elite rugby union?
(2019)The aim of this study was to use video evidence of tackles in elite level rugby union to identify ball carrier proficiency characteristics, for both lower and upper body tackles, that have a higher propensity to result in ...
