Now showing items 1-2 of 2

    • Chemistry and Biology studies on anti-inflammiatory bile acid derivatives 

      LIU, SU (Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2019)
      Abstract The objective of the dissertation is to clarify the potency, cytotoxicity and metabolism of novel steroidal anti-inflammatory compounds in the treatment inflammatory bowel disease (IBD). Biochemical methods with ...
    • Understanding the Role of IL-36 Family Cytokines in Paediatric IBD 

      Leon, Gemma (Trinity College Dublin. School of Medicine. Discipline of Immunology, 2021)
      Despite significant therapeutic advances, the global incidence of Inflammatory Bowel Diseases (IBD) continues to rise, with approximately 25% of these cases reported in childhood and adolescence. Aberrant CD4+ TΗ cell ...