RSS 1.0School of Pharmacy and Pharmaceutical Sciences
Academic/Research Units within this Academic/Research Unit
-
Pharmaceutical Chemistry
Pharmaceutical Chemistry -
Pharmaceutics & Pharmaceutical Technology
Pharmaceutics & Pharmaceutical Technology -
Pharmacognosy
Pharmacognosy -
Pharmacology
Pharmacology -
Pharmacy and Pharmaceutical Sciences
Pharmacy and Pharmaceutical Sciences
Recent Submissions
-
Benefit of inhalation aromatherapy as a complementary treatment for stress and anxiety in a clinical setting - A systematic review
(2023)Objective: The purpose of this systematic review is to ascertain the impact of inhalation aromatherapy on stress and anxiety in clinical settings. Methods: A search strategy was developed using various databases. ... -
Investigation of the Impact of Inhalation Aromatherapy on Relaxation and Wellbeing in a Young Adult Population
(2024)Background and Purpose: Aromatherapy is the systematic use of essential oils extracted from plants to support health and wellbeing. Recent clinical studies have shown that aromatherapy has potential benefits as a ... -
A Comparison of Spray drying and Liquid Antisolvent Co-precipitation for the Generation of Two- and Three- component Amorphous Solid Dispersions
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2024)The thesis focuses on the use of different manufacturing techniques for the generation of amorphous solid dispersions (ASDs) for the enhancement of the solubility of model compounds. ASDs with hydrochlorothiazide (HCTZ) ... -
Exploring the potential impact of collaborative medicines optimisation involving pharmacogenomic testing and general practice pharmacists in primary care in Ireland
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, School of Pharmacy and Pharmaceutical Sciences, University of Dublin, Trinity College, 2024)Introduction People are living longer, but not necessarily in better health. The ageing population coupled with the rise in chronic conditions has led to many older people being prescribed polypharmacy, which may not always ... -
Public and Patient Involvement with a Descriptive Qualitative Study to Explore Household Medication Safety in People who were Cocooning during Covid-19.
(2021)Household medication safety during a pandemic. • Medication use is the most common healthcare intervention. • During the COVID-19 pandemic, people who are staying at home and reducing contact with other people for long ... -
Assessment of milk extracellular vesicle (EV) in vitro bioactivity
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, School of pharmacy and pharmaceutical science, 2024)Extracellular Vesicles (EVs) are small particles involved in cell-to-cell communication. They have been identified in numerous biological fluids, including milk. Milk EVs serve to communicate between mother and infant, ... -
Pharmaceutical Solid Forms and Formulations for Enhanced Solubility and Dissolution: Cocrystals, Salts, and Crystalline Solid Dispersions
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2024)This thesis focuses on the development, manufacture, and characterisation of cocrystals and salts and their formulations, to enhance the solubility and dissolution of poorly soluble drugs. Three poorly soluble active ... -
Using in vitro and in silico approaches to investigate ibuprofen particulate and formulation dissolution behaviour under different hydrodynamic conditions.
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2024)This work investigated the effect of fluid velocity and medium viscosity on the dissolution of ibuprofen powder and ibuprofen immediate release tablets in vitro, in the paddle apparatus and the flow-through apparatus, and ... -
The treatment of obesity using magneto -mechanical effect
Obesity is a very prevalent condition that can be very often associated with the development of comorbidities, such as insulin resistance, hypertension, and hyperlipidaemia that can lead to cardiovascular and cerebrovascular ... -
A mixed-methods approach to explore the association between age and medication -related problems among adults
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2024)General introduction Much attention was focused on the ageing phenomenon and how to improve the quality of life in older people. Medication-related problems (MRPs) can potentially lead to hospital admissions, increased ... -
Guided by theory, grounded in practice: evidence-based development of teaching resources for multisite interprofessional education
(Trinity College Dublin, 2023) -
Chemotherapy drug scheduling for the induction treatment of patients with acute myeloid leukemia
(2014)Leukemia is an immediately life-threatening cancer wherein immature blood cells are overproduced, accumulate in the bone marrow (BM) and blood and causes immune and blood system failure. Treatment with chemotherapy can ... -
Long-term cytokine-free expansion of cord blood mononuclear cells in three-dimensional scaffolds
(2011)Cord blood expansion ex vivo can be achieved in liquid suspension through the addition of cytokines at the expense of often undesirable cell differentiation. In order to derive a cytokine-free dynamic culture system, we ... -
The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia
(2010)Acute myeloid leukaemia (AML) is a cancer of haematopoietic cells that develops in three-dimensional (3-D) bone marrow niches in vivo. The study of AML has been hampered by lack of appropriate ex vivo models that mimic ... -
Development and preliminary evaluation of OPTI-3S: A deprescribing support tool for hospitalised frail older adults.
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2024)Introduction: In frail older people, polypharmacy (5 or more regular prescribed medicines) and the prescription of potentially inappropriate medicines (PIMs) are known to be prevalent and linked to negative clinical outcomes. ... -
Dynamic human erythropoiesis in a three-dimensional perfusion bone marrow biomimicry
(2019)Traditional culture systems for human erythropoiesis lack microenvironmental niches, spatial marrow gradients and dense cellularity rendering them incapable of effectively translating marrow physiology ex vivo. Herein, a ... -
Mesoporous Silica Nanocarriers for triggered drug delivery in the treatment of cancer
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Cancer is the second leading cause of death globally, accounting for 10 million deaths in 2020. Cancer chemotherapy is currently limited by a high systemic toxicity that occurs as a result of high systemic dosing and the ... -
A theory-based exploration of the medicines management process provided to older people residing in the nursing home setting in the Republic of Ireland
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Introduction While the population is ageing globally, this does not necessarily mean that they are living healthier. The multimorbidity and polypharmacy in the older population (age> 65 years) increases their risk of ...
