Browsing School of Engineering by Subject "3D bioprinting"
Now showing items 1-8 of 8
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3D Bioprinted Cartilaginous Templates as Developmentally Inspired Implants for Large Bone Defect Regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2022)Whilst bone possesses an inherent capacity for regeneration, defects above a critical size cannot heal on their own. Damaged or diseased bone can be treated using autografts or a range of different bone grafting biomaterials, ... -
3D bioprinting of cartilage-mimetic implants for biological joint resurfacing
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)A major challenge in the field of tissue engineering and regenerative medicine is the development of effective therapies for treating large cartilage or osteochondral defects and ultimately regenerating whole osteoarthritic ... -
3D Bioprinting of Developmentally Inspired Templates for Bone and Joint Regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2018)There is an urgent need to develop alternatives to synthetic joint prosthesis to promote the regeneration of diseased osteoarthritic joints. Cell based therapies have shown promise for repairing cartilage and bone; however, ... -
Affinity-bound growth factor within sulfated interpenetrating network bioinks for bioprinting cartilaginous tissues
(2021)3D bioprinting has emerged as a promising technology in the field of tissue engineering and regenerative medicine due to its ability to create anatomically complex tissue substitutes. However, it still remains challenging ... -
The Development of a Novel 3D Bioprinting Strategy to Drive Vascularisation, and its Application for Bone Tissue Engineering
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)One of the major challenges facing the field of tissue engineering today is vascularisation. Without a system in place to circulate oxygen, nutrients and metabolites, the size of many tissue engineered constructs is ... -
Integrating melt electrowriting and inkjet bioprinting for engineering structurally organized articular cartilage
(2022)Successful cartilage engineering requires the generation of biological grafts mimicking the structure, composition and mechanical behaviour of the native tissue. Here melt electrowriting (MEW) was used to produce arrays ... -
Reinforcing interpenetrating network hydrogels with 3D printed polymer networks to engineer cartilage mimetic composites
(2020)Engineering constructs that mimic the complex structure, composition and biomechanics of the articular cartilage represents a promising route to joint regeneration. Such tissue engineering strategies require the development ... -
Towards 3D bioprinting of anatomically accurate, mechanically reinforced cartilage templates for biological joint resurfacing
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2018)Osteoarthritis (OA) is a pervasive disease worldwide which affects the articular cartilage and the underlying bone in synovial joints such as the knee. Currently, the only treatment for a severely degenerated knee joint ...
