Browsing Psychiatry by Title
Now showing items 435-437 of 437
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An X11[alpha]/FSBP complex represses transcription of the GSK3[beta] gene promoter.
(2010)X11? is a neuronal adaptor protein that interacts with the amyloid precursor protein (APP) via a centrally located phosphotyrosine binding (PTB) domain to inhibit production of A? peptide that is deposited in Alzheimer's ... -
X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice.
(2009)Increased production and deposition of amyloid ?-protein (A?) are believed to be key pathogenic events in Alzheimer?s disease. As such, routes for lowering cerebral A? levels represent potential therapeutic targets for ... -
ZNF804A risk allele is associated with relatively intact gray matter volume in patients with schizophrenia
(Elsevier, 2010)ZNF804A rs1344706 is the first genetic risk variant to achieve genome wide significance for psychosis. Following earlier evidence that patients carrying the ZNF804A risk allele had relatively spared memory function compared ...
