Browsing Psychiatry by Title
Now showing items 338-357 of 437
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On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia
(Elsevier, 2011)Pathological 43-kDa transactive responsive sequence DNA-binding protein (TDP-43) has been recognized as the major disease protein in amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration with ubiquitin ... -
Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors.
(2011)Oxidative stress is implicit in the pathological changes associated with glaucoma. The purpose of this study was to compare levels of oxidative stress in glial fibrillary acid-negative protein (GFAP) lamina cribrosa (LC) ... -
Pathways to Child Hospitalization
(Eastern Health Board. Dublin, 1988) -
Perinatal Depression and Children's Developmental Outcomes at 2 and 3 Years Postpartum
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)Depression is the most common perinatal psychiatric disorder and has been associated with a range of adverse outcomes for children, parents and overall family functioning. The current thesis sought to build on existing ... -
Phenotypic and molecular genetic analysis of autism
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2010)Autism is an early onset neurodevelopmental disorder affecting three core areas of behaviour - communication, social interaction and restricted repetitive behaviour. Although family and twin studies indicate a genetic ... -
The phenotypic manifestations of rare genic CNVs in autism spectrum disorder.
(2014)Significant evidence exists for the association between copy number variants (CNVs) and Autism Spectrum Disorder (ASD); however, most of this work has focused solely on the diagnosis of ASD. There is limited understanding ... -
PICLS Staff Manual
(Prison Inreach & Court Liaison Service, NFMHS Central Mental Hospital, 2017) -
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.
(2014)Bipolar disorder and schizophrenia are two often severe disorders with high heritabilities. Recent studies have demonstrated a large overlap of genetic risk loci between these disorders but diagnostic and molecular ... -
Predictability and construct validity of oppositional defiant disorder in children and adolescents with ADHD combined type.
(Cambridge University Press, 2010)Background. Oppositional defiant disorder (ODD) is frequently co-occurring with attention deficit hyperactivity disorder (ADHD) in children and adolescents. Because ODD is a precursor of later conduct disorder (CD) ... -
Predictability of oppositional defiant disorder and symptom dimensions in children and adolescents with ADHD combined type
(Cambridge University Press, 2010)Background Oppositional defiant disorder (ODD) is frequently co-occurring with attention deficit hyperactivity disorder (ADHD) in children and adolescents. Because ODD is a precursor of later conduct disorder (CD) and ... -
Preferential Transmission of Paternal Alleles at Risk Genes in Attention Deficit/Hyperactivity Disorder
(2005)Family, twin, and adoption studies have demonstrated a significant genetic contribution to the etiology of attention-deficit/hyperactivity disorder (ADHD). Pharmacological, neuroimaging, and animal-model findings suggest ... -
Prognostic factors of 2-year outcomes of patients with comorbid bipolar disorder or depression with alcohol dependence: Importance of early abstinence
(2013)Aims: To investigate the prognostic factors that determine 2-year outcomes in a group of alcohol-dependent patients with depression or bipolar disorder who were treated in an intensive 4-week inpatient programme. Methods: This ... -
Prospective observational cohort study of 'treatment as usual' over four years for patients with schizophrenia in a national forensic hospital.
(2018)Background: We evaluated change in response to multi-modal psychosocial ‘treatment as usual’ programs offered within a forensic hospital. Methods: Sixty nine patients with a diagnosis of schizophrenia or schizoaffective ... -
Prospective study of factors influencing conditional discharge from a forensic hospital: the DUNDRUM-3 programme completion and DUNDRUM-4 recovery structured professional judgement instruments and risk
(2013)Background We set out to examine whether structured professional judgement instruments DUNDRUM-3 programme completion (D-3) and DUNDRUM-4 recovery (D-4) scales along with measures of risk, mental state and global function ...
