Browsing Psychiatry by Title
Now showing items 283-302 of 437
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Mental Capacity for Treatment Decisions in Psychiatry Inpatients
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2024)This research aimed to assess the prevalence of mental capacity for treatment decisions in psychiatry inpatients in Ireland and elucidate the relationship, if any, between mental capacity and key clinical and demographic ... -
Mental disorders in the community dwelling elderly
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2000)The elderly population is increasing both in numbers and as a proportion of the overall population. Mental disorders are common among the elderly. Most older people with mental disorders live in the community and attend ... -
Mental health in Northern Malawi : a cultural perspective
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2002)This thesis seeks to address a theoretical question: What is the experience of people with a mental disturbance, when they are introduced to a health care system which is ontologically distinct from their own cultural ... -
Mental health problems in children with prader-willi syndrome.
(2012)BACKGROUND: Prader-Willi Syndrome (PWS) is a genetically determined neurodevelopmental disorder, which occurs in approximately one in 22000 births. AIMS: This study aimed to investigate psychiatric characteristics of ... -
Mental Illness in Irish Prisoners
(National Forensic Mental Health Service, Dundrum, Dublin 14, Ireland, 2004-12)This is the first systematic and representative survey of psychiatric morbidity in the Irish Prison population, using standardised research diagnostic methods. Five samples have been compiled, including 7% of all men ... -
Mental state decoding v. mental state reasoning as a mediator between cognitive and social function in psychosis
(The Royal College of Psychiatrists, 2008)Theory of mind deficits in schizophrenia have been parsed into mental state reasoning and mental state decoding components. We report that mental state decoding as measured by the `Eyes task? better predicted social function ... -
Mental state decoding versus mental state reasoning as a mediator between cognitive and social function in psychosis
(2008)Theory of mind deficits in schizophrenia have been parsed into mental state reasoning and mental state decoding components. We report that mental state decoding as measured by the `Eyes task? better predicted social ... -
Methodological issues in event-related fMRI
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2005)Functional magnetic resonance imaging (fMRI) is a very powerful tool for localising psychological functions to specific brain areas. Recently, there has been a surge of interest in determining the functional differences ... -
Methyl-CpG2-binding protein 2 mediates overlapping mechanisms across brain disorders
(2020)MECP2 and its product, Methyl-CpG binding protein 2 (MeCP2), are mostly known for their association to Rett Syndrome (RTT), a rare neurodevelopmental disorder. Additional evidence suggests that MECP2 may underlie other ... -
Microduplications of 16p11.2 are associated with schizophrenia
(Nature, 2009)Recurrent microdeletions and microduplications of a 600-kb genomic region of chromosome 16p11.2 have been implicated in childhood-onset developmental disorders. We report the association of 16p11.2 microduplications with ... -
Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms?
(2010)Mental disorders are a major cause of long-term disability and are a direct cause of mortality, with approximately 800.000 individuals dying from suicide every year worldwide ? a high proportion of them related to major ... -
MIR137HG risk variant rs1625579 genotype is related to corpus callosum volume in schizophrenia
(2015)Genome-wide association studies implicate the MIR137HG risk variant rs1625579 (MIR137HGrv) within the host gene for microRNA-137 as a potential regulator of schizophrenia susceptibility. We examined the influence of ... -
The molecular determinant of IGF-1(Mecasermin)action in Rett Syndrome Patients
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2018)Abstract This is a preliminary investigation of effects of insulin-like growth factor-1 (IGF-1) treatment on differential gene expression (DGE) of whole blood samples from Rett syndrome (RTT) patients. Samples were ... -
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).
(2014)It has long been recognized that generalized deficits in cognitive ability represent a core component of schizophrenia (SCZ), evident before full illness onset and independent of medication. The possibility of genetic ... -
Molecular genetics investigations in autism
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2004)This research thesis involved the establishment and management of a research group in autism genetics in addition to the collection of an autism sample of parent-child trios. A well-characterised sample of individuals with ... -
The Molecular Mechanisms of rhIGF1 in the Treatment of Rett Syndrome and Related Disorders: Studies in Patients, Mouse and Cellular Models
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2022)Recombinant human Insulin-like Growth Factor 1 (rhIGF1) is an approved treatment for growth failure and IGF1 deficiency. IGF1 has multiple functions in the body including growth, cell survival, metabolism, ageing and ...
