Browsing Dental Science (Scholarly Publications) by Date of Publication
Now showing items 1-20 of 138
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Candida dubliniensis: An update
(1999)The increased incidence of fungal infections during the last decade has been well-documented. Given that one of the most important factors contributing to this phenomenon is the increased numbers of immunocompromised ... -
COMPARATIVE GENOMICS USING CANDIDA ALBICANS DNA MICROARRAYS REVEALS ABSENCE AND DIVERGENCE OF VIRULENCE ASSOCIATED GENES IN CANDIDA DUBLINIENSIS
(2004)Candida dubliniensis is a pathogenic yeast species closely related to Candida albicans. However, it is less frequently associated with human disease and displays reduced virulence in animal models of infection. We have ... -
Reduced azole susceptibility in genotype 3 C. dubliniensis isolates associated with increased CdCDR1 and CdCDR2 expression.
(2005)Candida dubliniensis is a recently identified yeast species primarily associated with oral carriage and infection in HIV-infected individuals. The species can be divided into at least four genotypes on the basis of the ... -
AZOLE SUSCEPTIBILITY AND RESISTANCE IN CANDIDA DUBLINIENSIS
(2005)Candida dubliniensis is a recently described species of pathogenic yeast that shares many phenotypic features with Candida albicans. It is primarily associated with oral colonization and infection in HIV-infected individuals. ... -
NOVEL 5-FLUCYTOSINE-RESISTANT CLADE OF CANDIDA DUBLINIENSIS FROM SAUDI ARABIA AND EGYPT IDENTIFIED BY CD25 FINGERPRINTING.
(2005)DNA fingerprinting of Candida dubliniensis isolates using the species-specific probe Cd25 previously showed that this species consists of two distinct groups, termed Cd25 group I and Cd25 group II. The present study ... -
DIFFERENTIAL REGULATION OF THE TRANSCRIPTIONAL REPRESSOR NRG1 ACCOUNTS FOR ALTERED HOST CELL INTERACTIONS IN CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS
(2007)Candida dubliniensis is genetically closely related to C. albicans, but causes fewer infections in humans and exhibits reduced virulence and filamentation in animal models of infection. We investigated the role of the ... -
Lower filamentation rates of Candida dubliniensis contribute to its lower virulence in comparison with Candida albicans
(Elsevier, 2007)Candida albicans and Candida dubliniensis are very closely related yeast species. In this study, we have conducted a thorough comparison of the ability of the two species to produce hyphae and their virulence in two ... -
DIFFERENTIAL REGULATION OF THE TRANSCRIPTIONAL REPRESSOR NRG1 ACCOUNTS FOR ALTERED HOST CELL INTERACTIONS IN CANDIDA ALBICANS AND CANDIDA DUBLINIENSIS
(Blackwell Publishing, 2007-09)Candida dubliniensis is genetically closely related to C. albicans, but causes fewer infections in humans and exhibits reduced virulence and filamentation in animal models of infection. We investigated the role of the C. ... -
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
(2008)Abstract: Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually(1). To identify genetic factors that modify disease risk, we conducted a genome- wide association study by ... -
MULTILOCUS SEQUENCE TYPING REVEALS THAT THE POPULATION STRUCTURE OF Candida dubliniensis IS SIGNIFICANTLY LESS DIVERGENT THAN THAT OF Candida albicans
(2008)he pathogenic yeast Candida dubliniensis is phylogenetically very closely related to Candida albicans, and both species share many phenotypic and genetic characteristics. DNA fingerprinting using the species-specific probe ... -
Multilocus sequence typing reveals that the population structure of Candida dubliniensis is significantly less divergent than that of Candida albicans.
(2008)The pathogenic yeast Candida dubliniensis is phylogenetically very closely related to Candida albicans, and both species share many phenotypic and genetic characteristics. DNA fingerprinting using the species-specific probe ... -
AVIAN-ASSOCIATED AND HUMAN ISOLATES OF Candida dubliniensis ARE GENETICALLY DISTINCT
(2009)When Candida dubliniensis isolates obtained from seabird excrement and from humans in Ireland were compared by using multilocs sequence typing, 13 of 14 avian isolates were genetically distinct from human isolates. The ... -
A Ser29Leu SUBSTITUTION IN THE CYTOSINE DEAMINASE Fca1p IS RESPONSIBLE FOR CLADE-SPECIFIC 5-FLUCYTOSINE RESISTANCE IN Candida dubliniensis
(2009)The population structure of the opportunistic yeast pathogen Candida dubliniensis is composed of three main multilocus sequence typing clades (clades C1 to C3), and clade C3 predominantly consists of isolates from the ... -
Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress
(Wiley-Blackwell, 2009)Candida albicans is more pathogenic than Candida dubliniensis. However, this disparity in virulence is surprising given the high level of sequence conservation and the wide range of phenotypic traits shared by these two ... -
Head and neck squamous cell carcinoma in the young: a spectrum or a distinct group? Part 1.
(2009)While most head and neck squamous carcinoma (HNSCC) occurs in older people, an increasing number of young patients are being affected worldwide, with up to 5.5% <40. These are predominantly oral and oropharyngeal cancers. ... -
Head and neck squamous cell carcinoma in the young: a spectrum or a distinct group? Part 2.
(2009)A recent increase in the number of young patients (often nonsmokers) developing head and neck squamous cell carcinoma (HNSCC) has been documented, however, there remains no clear evidence to support the significance of any ... -
Purification and germination of Candida albicans and Candida dubliniensis chlamydospores cultured in liquid media
(2009-06-30)Candida albicans and Candida dubliniensis are the only Candida species that have been observed to produce chlamydospores. The function of these large, thick-walled cells is currently unknown. In this report we describe ... -
Differential filamentation of Candida albicans and C. dubliniensis is governed by nutrient regulation of UME6 expression
(2010)Candida dubliniensis is closely related to C. albicans, however it is responsible for fewer infections in humans and is less virulent in animal models of infection. C. dubliniensis forms fewer hyphae in vivo and this may ... -
LACK OF CYTOTOXICITY BY TRUSTWATER ECASOL? USED TO MAINTAIN GOOD QUALITY DENTAL UNIT WATERLINE OUTPUT WATER IN KERATINOCYTE MONOLAYER AND RECONSTITUTED HUMAN ORAL EPITHELIAL TISSUE MODELS
(2010)Summary: We previously showed that residual treatment of dental chair unit (DCU) supply water using the electrochemically-activated solution Trustwater Ecasol? (2.5 ppm) provided an effective long-term solution to the ...
