RSS 1.0Dental Science (Theses and Dissertations)
Recent Submissions
-
A clinical & laboratory investigation of the use of leukocyte and platelet-rich fibrin (L-PRF) in alveolar ridge preservation and management of peri-implant defects
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, Trinity College Dublin, School of Dental Science, 2025)Overall Aim of PhD: To evaluate the efficacy of leukocyte- and platelet-rich fibrin (L-PRF) in the management of both alveolar ridge preservation (ARP) and peri-implantitis defects. STUDY 1. Methods: A systematic review ... -
The Oral Health of the Irish Army
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2025)Background Dental services are provided in the Army for operational reasons as a means of collecting dental forensic charting and reducing the likelihood of a dental emergency. Recent data reporting the oral health of ... -
Environmental Impact of Personal Protective Equipment in Dental Services During COVID-19: A Life Cycle Assessment Approach
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2025)Objectives: COVID-19 has significantly influenced Personal Protective Equipment (PPE) use in dental services. This study quantifies the environmental impact of different PPE types used at Dublin Dental University Hospital ... -
Associations between early-life behaviours, current oral health behaviours and oral health among children in Brunei Darussalam and the recommendations for oral health prevention strategies
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, School of Dental Science, 2025)Background: There is limited evidence of inequalities in dental caries in deciduous dentition among children in Brunei Darussalam. Moreover, there is no evidence assessing the associations of early-life behaviours and ... -
A Randomised Controlled Clinical Trial investigating the effect of osseodensification on implant stability and marginal bone levels.
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2025)Osseointegration is a histologic term defined as the “direct structural and functional connection between living bone and the surface of a load-carrying dental implant”. Achieving successful osseointegration without the ... -
Diet and Oral Health of Elite Athletes in Ireland
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, Trinity College Dublin, the University of Dublin, 2025)Introduction: Previous research has indicated a high prevalence of untreated dental disease among elite athletes. Multiple factors may predispose athletes to a high-risk profile including frequent carbohydrate consumption, ... -
Investigation of the role of Mediator tail subunits in antifungal drug resistance and cellular aggregation in Candida species
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2025)Candida albicans is a commensal fungal pathogen that resides on various human mucosal surfaces (e.g. oral cavity) and can cause severe infection in immunocompromised individuals. Azole antifungal resistance in C. albicans ... -
Accuracy of Predicting Treatment Adjuncts for Patients Requiring Special Care Dentistry
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2025)Background: Predicting the correct treatment adjuncts in special care dentistry (SCD), such as non-pharmacological behavioural support, inhalation sedation, intravenous (IV) sedation, or general anaesthesia (GA), can be ... -
Characterisation of the role of the Candida albicans Tor1 Pathway in regulating flocculation biofilm formation & hyphal growth
(Trinity College (Dublin, Ireland). School of Dental Science, 2016)Candida species are responsible for a wide range of superficial and life threatening infections and are the fourth most common cause of nosocomial bloodstream infections. Candida albicans is an opportunistic pathogen that ... -
The role of hagB and hagC in the virulence of Porphyromonas gingivalis and indentifcation of putative novel virulence factors by Transposon-Seq
(Trinity College (Dublin, Ireland). School of Dental Science, 2016)The haemagglutinin genes of P. gingivalis are believed to play an important role in the virulence of the organism. A subset of these genes, namely hagB and hagC, are distinct from the other family members based on nucleotide ... -
A Large-Scale Investigation of the Molecular Epidemiology and Phylogenetics of Vancomycin-Resistant Enterococcus faecium from Irish Hospitals: A Microbial Genomics Approach
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)Enterococcus faecium is a commensal bacterium of the human gastrointestinal tract that has emerged as an important opportunistic pathogen, particularly in immunocompromised patients. Multi-drug resistant strains, notably ... -
The use of vertical bitewings compared to visual examination alone for dental caries diagnosis and treatment planning in paediatric dentistry
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, School of Dental Sciences, 2024)Aim: The aim of the present study was to evaluate the use of vertical bitewing radiographs (VBWs) compared to visual examination alone for caries diagnosis and treatment planning in children. Secondary aims included the ... -
The efficacy of Horizontal- Platelet Rich Fibrin (H-PRF) compared to Alveogyl in the treatment of alveolar osteitis: a randomised controlled trial
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)Objectives: To investigate the efficacy of treating alveolar osteitis with an autologous blood product, Horizontal Platelet Rich Fibrin (H-PRF) compared to Alveogyl, a conventional intra-alveolar dressing. Materials and ... -
Development of a core outcome set for third molar surgery
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, School of Dental Science, Trinity College Dublin, The University of Dublin, 2024)Introduction: Third molar surgery (TMS) is one of the most common operations in the world and a wealth of research is done in this field evaluating various interventions for the improvement of patient outcomes. In the ... -
Oral Health Data Analysis in National Child Cohort Surveys
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)Objectives: The objectives of this research were to: (1) summarise dental caries trends and evaluate effectiveness of community water fluoridation at National, Regional, and County- levels in the Republic of Ireland from ... -
Investigation into the Genotypes and Phenotypes of Fusobacterium nucleatum subsp. polymorphum Isolates Recovered from Oral Leukoplakia
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)Fusobacterium nucleatum is Gram negative anaerobe of the oral cavity, where it plays a key role as a bridging organism in the plaque biofilm between early colonisers of the tooth surface, such as streptococcal species, and ... -
The Oro-Nasal Cavity as an Endogenous Staphylococcal Reservoir for Diabetic Foot Ulcer Infections Investigated by Whole Genome-Sequencing and Disinfection of Debrided Foot Ulcer Tissues using Electrochemically-Activated Hypochlorous Acid Solution
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)Background and study purpose Type II diabetes mellitus is highly prevalent worldwide (approximately 6.3-10.5% of the global population), and in the population of the Republic of Ireland (9.5%), and continues to increase ... -
An investigation into molecular biomarkers of pulp inflammation and cell death and their potential use as a diagnostic tool.
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)The overarching aim of the thesis was to present a robust method of collecting and analysing pulpal blood, to inform quality biomarker discovery with the potential to detect the `threshold? between teeth amenable to vital ... -
An investigation of the hydraulic calcium silicate cement, Biodentine, as a vital pulp treatment material
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)A recent upsurge in the popularity of Vital Pulp Treatment (VPT) has been attributed to a deeper understanding of the pulp reparative processes, biomaterial development and technological advancement. The introduction of ... -
The multi-faceted effects of ethanol exposure on oral dysplastic and cancer cells.
(Trinity College Dublin. School of Dental Sciences. Discipline of Dental Science, 2024)Oral cancers (OC) are cancers that arise in several regions within the oral cavity such as the lips, gums, tongue, lining of the cheeks, and the floor or roof of the mouth. Approximately 400,000 cases were diagnosed worldwide ...
