A new variant of inflammatory bowel disease, provisionally termed "autistic enterocolitis" has been described in a cohort of children with autistic spectrum disorders. The intestinal pathology includes ileo-colonic ...

Research over the past number of decades has significantly advanced our understanding of the cell signalling effects that mediate a diverse array of cellular activities including cell proliferation, homeostasis and ...

Understanding the molecular mechanisms behind cancer cell proliferation and regulation is the key to discovering potential future successful therapies for cancer. The World Health Organisation estimates that 7.6 million ...

Thyroid carcinoma is the most common endocrine malignancy, with an incidence of approximately eighty cases per year in Ireland and thirty seven thousand cases per year in the United States. While thyroid cancer may be ...

Epithelial ovarian cancer is one of the most common cancers in women and the leading cause of death from gynaecological malignancy in the western world. Approximately 205,000 cases of ovarian cancer are diagnosed worldwide ...

Prognosis in thyroid carcinoma is usually assessed on the basis of criteria, which include patient age and histological type, grade and stage of tumour. It is well recognised, however, that while occasional tumours with ...

Papillary thyroid carcinomas (PTC) are the most frequently occurring type of thyroid malignancy (85%-90%). PTC affects females more frequently than males, with a ratio of 3:1 and can be present in any age group, the mean ...

Despite the introduction of the Papanicolaou (Pap) test carcinoma of the cervix remains one of the most common malignancies amongst women worldwide. It is hoped that the use of HPV testing and molecular biomarkers in ...

Archival Formalin-Fixed, Paraffin-Embedded (FFPE) tissue samples represent an invaluable source of human tissue for gene expression analysis. They are the most abundant and readily available materials and generally well ...

Papillary thyroid carcinoma is the most comm on thyroid malignancy, with an incidence of <100 cases per year in Ireland and 16,000 cases per year in the U.S. Incidence is increasing with a global estimate of half a million ...