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Assessing the effects of coenzyme QIO in schizophrenia & schizoaffective disorder: a randomised, placebo controlled trial
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2020)
Background: Schizophrenia is a complex, heterogeneous, neurodevelopmental disorder. Cognitive impairments and negative symptoms such as avolition and asociality are prevalent in the majority of patients with a diagnosis ...
Age-related hearing loss and neurocognitive function: Normal and pathological processes in cognitive ageing
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2018)
This thesis investigates age-related hearing loss (ARHL) as a potential biomarker and risk factor for cognitive decline and dementia. Two reviews were conducted to examine the evidence for an association in the epidemiological ...
The Contribution of Additional Genetic Variation to CNV Carrier Cognitive and Neurodevelopmental Outcomes
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2023)
Many copy number variants (CNV) are strongly associated with neurodevelopmental disorders (NDDs) such as autism, intellectual disability/developmental delay (ID/DD) and schizophrenia. CNVs are large genomic deletions or ...