Browsing Psychiatry (Theses and Dissertations) by Sponsor "Science Foundation Ireland (SFI)"
Now showing items 1-2 of 2
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Developing pedigree-based strategies to analyse whole genome sequencing data for complex disorders: learning from schizophrenia
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2023)Complex genetic disorders are impacted by a range of DNA variation. Next generation sequencing (NGS) allows for the direct examination of this variation, but large sample numbers are required to identify rare variants in ... -
Exploring the molecular mechanisms of Rett syndrome
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2020)Rett Syndrome (RTT) is a severe neurological disorder that onsets between 6 to 18 months of age, after a period of apparently normal development. RTT affects approximately 1 in every 10000 to 15000 live births and is ...
