Browsing Zoology by Author "Prendergast, Patrick"
Now showing items 1-3 of 3
-
Biophysical stimuli induced by passive movements compensate for lack of skeletal muscle during embryonic skeletogenesis
(University of Edinburgh (datashare), 2011)In genetically modified mice with abnormal skeletal muscle development, bones and joints are differentially affected by the lack of skeletal muscle.We hypothesise that unequal levels of biophysical stimuli in the ... -
Developing bones are differentially affected by compromised skeletal muscle formation
(University of Edinburgh (datashare), 2010)Mechanical forces are essential for normal adult bone function and repair, but the impact of prenatal muscle contractions on bone development remains to be explored in depth in mammalian model systems. In this study, we ... -
Identification of Mechanosensitive Genes during Embryonic Bone Formation.
(2008)Although it is known that mechanical forces are needed for normal bone development, the current understanding of how biophysical stimuli are interpreted by and integrated with genetic regulatory mechanisms is limited. ...
