Browsing by Subject "Frailty"
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Alluvial visualization and computation of probabilities of transitions in frailty index states over an 8-year period using multi-state Markov models
(2021)The Frailty Index (FI) is an operationalization of frailty in older adults based on the accumulation of health deficits. FI cut-offs define the non-frail, prefrail and frail states. We described longitudinal transitions ... -
The association of geriatric syndromes with hospital outcomes
(2017)BACKGROUND: Frailty, history of dementia (HoD), and acute confusional states (ACS) are common in older patients admitted to hospital. OBJECTIVE: To study the association of frailty (≥6 points in the Clinical Frailty Scale ... -
Building resilience and reversing frailty: a randomised controlled trial of a primary care intervention for older adults
(2023)Background: There is a need for effective primary care interventions that help older people combat frailty and build resilience. Objective: To study the effectiveness of an optimised exercise and dietary protein ... -
Cardiovascular risk factors and frailty in a cross-sectional study of older people: implications for prevention.
(2018)Objective: to examine the associations of cardiovascular disease (CVD) and cardiovascular risk factors with frailty. Design: a cross-sectional study. Setting: the Irish Longitudinal Study on Ageing (TILDA). Participants: ... -
Changes in Muscle Strength and Physical Function in Older Patients During and After Hospitalisation: a Prospective Repeated-Measures Cohort Study
(2020)Aim: To investigate changes in knee-extension strength and physical function in older adults during and after acute hospital admission, and the contributions of illness severity, frailty and sedentary activity to changes ... -
Circulating micronutrient biomarkers are associated with three measures of frailty: Evidence from The Irish Longitudinal Study on Ageing (TILDA).
(2019)Objectives: To examine the associations between 3 frailty instruments and circulating micronutrients in a large representative sample of older adults. Design: Cross-sectional data from a nationally representative cohort ... -
Clinical frailty independently predicts early mortality after ischaemic stroke
(2020)Background: Clinical frailty is an important syndrome for clinical care and research, independently predicting mortality and rates of institutionalisation in a range of medical conditions. However, there has been little ... -
Comprehensive geriatric assessment and clinical outcomes of frail older adults with diffuse large B-cell lymphoma: a metanalysis
(2023)Introduction. Comprehensive geriatric assessment (CGA) is used to personalize cancer treatments in frail older adults. However, its utility to guide treatments in frail older patients with diffuse large B-cell lymphoma ... -
Delaying and reversing frailty: a systematic review of primary care interventions
(2019)Background: Recommendations for routine frailty screening in general practice are increasing as frailty prevalence grows. In England, frailty identification became a contractual requirement in 2017. However, there is little ... -
Development of a Frailty Index in the Irish Hip Fracture Database
(2022)Introduction In older people, hip fracture can lead to adverse outcomes. Frailty, capturing biological age and vulnerability to stressors, can indicate those at higher risk. We derived a frailty index (FI) in the Irish ... -
Evaluation of a 3-Item Health Index in Predicting Mortality Risk: A 12-Year Follow-Up Study
(2023)This study was carried out using a large cohort (N = 4265; 416 deceased) of older, community-dwelling adults from The Irish Longitudinal Study on Ageing (TILDA). The study compared the performance of a new 3-item health ... -
Evaluation of the Timed Up and Go test for screening vulnerability and frailty in older cancer patients
(2023)Introduction. The need for comprehensive geriatric assessment (CGA) in older adults with cancer is increasing, which makes it necessary to have a screening instrument to identify those who would benefit from this ... -
Feasibility of a Broad Test Battery to Assess Physical Functioning Limitations of People Experiencing Homelessness
(2021)Background: People who are homeless experience poor health. Reflective of overall health and factors such as acquired injuries, physical ability or functioning is often low among people who are homeless, but there is a ... -
Feasibility of Telephone Follow-Up after Critical Care Discharge
(2020)Background: Critical care has evolved from a primary focus on short-term survival, with greater attention being placed on longer-term health care outcomes. It is not known how best to implement follow-up after critical ... -
Frail by Different Measures: A Comparison of 8-year Mortality in The Irish Longitudinal Study on Ageing (TILDA)
(2021)Purpose: We compared the ability of four frailty identification tools (frailty phenotype: FP; FRAIL scale; 32-item Frailty Index: FI; and Clinical Frailty Scale: CFS) to predict 8-year mortality in TILDA. Methods: We ... -
Frail by four different measures and new adverse events from lower blood pressure control in hypertensive older adults: a 2-year prospective study in The Irish Longitudinal Study on Ageing (TILDA)
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Frail by four different measures and new adverse events from lower blood pressure control in hypertensive older adults: a 2-year prospective study in The Irish Longitudinal Study on Ageing (TILDA) Student: Patrick O?Donoghue ... -
The frailty index in Europeans: assocation with age and mortality.
(2012)BACKGROUND: the frailty index (FI) is an approach to the operationalisation of frailty based on accumulation of deficits. It has been less studied in Europeans. OBJECTIVE: to construct sex-specific FIs from a large ...
