• 

  In vivo and in vitro mechanistic studies on targeting of lipophilic compounds to the intestinal lymphatics using lipid-based vehicles 

  Lawless, Emma C. (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2005)

  The aim of the experiments conducted in this thesis was to investigate the effect of a range of lipid-based vehicles on the intestinal lymphatic transport of triglycerides and of two lipophilic compounds- DDT and cyclosporine, ...
• 

  Development of novel cyclodextrins as non-viral gene delivery vectors and assessment of differentiated cell culture models to predict in vivo gene expression 

  Cryan, Sally-Ann (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2002)

  The aims of this thesis were to examine the use of differentiated cell culture systems in the in vitro assessment of non-viral gene delivery systems and to investigate the use of commercial and novel cyclodextrins as vectors ...
• 

  Factors affecting the pharmacotherapeutic management of chronic non-malignant pain in ageing and elderly populations in Ireland 

  Kennedy, Mary-Claire (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2015)

  Chronic non-malignant pain (CNMP) has emerged as a global health priority due to the prevalence, complexity and presentation of the condition across all age- groups, social classes and ethnicities. There is a high prevalence ...
• 

  The use of the Caco-2 cell culture model to investigate lipid vehicle effects on lipid metabolism and drug permeation 

  Seeballuck, Fergal (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2004)

  The aim of this thesis was to assess the usefulness of the Caco-2 model for screening lipid vehicle excipient effects on intestinal lipoprotein production and secretion, with emphasis on chylomicron secretion. In addition, ...
• 

  Use of halloysite for agrochemical applications 

  Salter, Anne Elizabeth (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2004)

  The focus of this thesis was to develop two products for use in agrochemical applications, using the naturally occurring microtubular mineral, halloysite. Firstly, it was necessary to obtain a highly tubular grade of the ...

View more