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Genetics
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School of Genetics & Microbiology
Genetics
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FARES, MARIO ALI (14)
WOLFE, KENNETH (1)
Subject
Genetics (3)
amino acid analysis; article; biogenesis; controlled study; convergent evolution; Escherichia coli; evolutionary adaptation; functional proteomics; genetic association; genetic conservation; genetic variability; host pathogen interaction; nonhuman; phylogeny; protein function; protein processing; ribosome; symbiosis; adaptation; bacterium; classification; cluster analysis; computer program; energy metabolism; metabolism (1)
amino acid; chaperonin; chaperonin 1; chaperonin 2; chaperonin 3; regulator protein; unclassified drug (1)
Candida glabrata (1)
Chicken (1)
co-evolution (1)
Comparative genomics has become a real tantalizing challenge in the postgenomic era. This fact has been mostly magnified by the plethora of new genomes becoming available in a daily bases. The overwhelming list of new genomes to compare has pushed the field of bioinformatics and computational biology forward toward the design and development of methods capable of identifying patterns in a sea of swamping data noise. Despite many advances made in such endeavor, the ever-lasting annoying exceptions to the general patterns remain to pose difficulties in generalizing methods for comparative genomics. In this review, we discuss the different tools devised to undertake the challenge of comparative genomics and some of the exceptions that compromise the generality of s uch methods. We focus on endosymbiotic bacteria of insects because of their genomic dynamics peculiarities when compared to free-living organisms (1)
Corrigendum (1)
Darwinian evolution (1)
Evolution, Evolvability, Plasticity, RNA structure, Robustness, Small RNA, Thermodynamics (1)
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2013 (1)
2012 (4)
2011 (1)
2010 (2)
2009 (3)
2008 (1)
2007 (1)
2003 (1)
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Science Foundation Ireland (2)
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Structural Calibration of the Rates of Amino Acid Evolution in a Search for Darwin in Drifting Biological Systems.
FARES, MARIO ALI
(
Oxford University Press
,
2010
)
Corrigendum to "The tale of a modern animal plague: Tracing the evolutionary history and determining the time-scale for foot and mouth disease virus" [Virology 382 (2008) 250-256] (DOI:10.1016/j.virol.2008.09.011)
FARES, MARIO ALI
(
2009
)
Proteome-Wide Analysis of Functional Divergence in Bacteria: Exploring a Host of Ecological Adaptations
FARES, MARIO ALI
(
2012
)
The Roles of Whole-Genome and Small-Scale Duplications in the Functional Specialization of Saccharomyces cerevisiae Genes
FARES, MARIO ALI
(
2013
)
Evolutionary rate and duplicability in the Arabidopsis thaliana protein-protein interaction network
FARES, MARIO ALI
(
2012
)
Molecular evolution of psbA gene in ferns: Unraveling selective pressure and co-evolutionary pattern
FARES, MARIO ALI
(
2012
)
In silico identification of functional divergence between the multiple groEL gene paralogs in Chlamydiae
FARES, MARIO ALI
(
2007
)
Describing the structural robustness landscape of bacterial small RNAs
FARES, MARIO ALI
(
2012
)
Why should we care about molecular coevolution?
FARES, MARIO ALI
(
2008
)
Computational Biology Methods and Their Application to the Comparative Genomics of Endocellular Symbiotic Bacteria of Insects
FARES, MARIO ALI
(
2009
)
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