Browsing School of Pharmacy and Pharmaceutical Sciences by Author "Wang, Jun"
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The design, synthesis and biological evaluation of novel barbiturate-based MMP inhibitors
Wang, Jun (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2010)Matrix metalloproteinases (MMPs) are a group of Zn-dependent endopeptidases that participate in many diseases. Two MMPs, MMP-2 and MMP-9, which are especially associated with inflammatory diseases and tumor metastasis have ...