Browsing School of Pharmacy and Pharmaceutical Sciences by Author "O'BOYLE, NIAMH"
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Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents
LLOYD, DAVID; NATHWANI, SEEMA; MCCABE, THOMAS; MEEGAN, MARY; GREENE, LISA; O'BOYLE, NIAMH; ZISTERER, DANIELA (2010) -
Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
MEEGAN, MARY; GREENE, LISA; O'BOYLE, NIAMH; MCCABE, THOMAS; ZISTERER, DANIELA; LLOYD, DAVID (2011)A series of azetidin-2-ones substituted at positions 2, 3 and 4 of the azetidinone ring scaffold were synthesised and evaluated for antiproliferative, cytotoxic and tubulin binding activity. In these compounds, the cis ...